USP8 ELISA Kits

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation.

Data Quality
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Type
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    Kit
Antigen
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Reactivity
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Application
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Method Type
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Analytical Method
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Detection Method
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Plate
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Sample
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4 Products
Pre-coated, Samples: Plasma, Serum
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range0.313-20 ng/mL
Order details Cat. No. ABIN1117711
$630.00
96 tests
Plus shipping costs $45.00
Delivery in 12 to 14 Business Days
Pre-coated, Samples: Cell Lysate, Tissue Homogenate
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range0.31 ng/mL - 20 ng/mL
Order details Cat. No. ABIN420762
$736.84
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
Pre-coated, Samples: Cell Lysate, Tissue Homogenate
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range0.312 ng/mL - 20 ng/mL
Order details Cat. No. ABIN1573011
$908.41
Plus shipping costs $45.00
Delivery in 15 to 17 Business Days
Pre-coated, Samples: Cell Lysate, Tissue Homogenate
ReactivityHuman
Detection MethodColorimetric, Sandwich ELISA
Detection Range0.312 ng/mL - 20 ng/mL
Order details Cat. No. ABIN5659745
$971.15
96 tests
Plus shipping costs $45.00
Delivery in 8 to 12 Business Days
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USP8 Antigen Profile

Protein Summary

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.

Gene names and symbols associated with USP8

  • ubiquitin carboxyl-terminal hydrolase 8 (LOC9310109) antibody
  • ubiquitin carboxyl-terminal hydrolase 8 (MGYG_00369) antibody
  • ubiquitin specific peptidase 8 (USP8) antibody
  • ubiquitin specific peptidase 8 (Usp8) antibody
  • AI574262 antibody
  • AW557536 antibody
  • HumORF8 antibody
  • mKIAA0055 antibody
  • Ubpy antibody

Protein level used designations for USP8

ubiquitin carboxyl-terminal hydrolase 8 , ubiquitin-specific-processing protease 8 , ubiquitin specific peptidase 8 , ubiquitin carboxyl-terminal hydrolase 8-like , deubiquitinating enzyme 8 , hUBPy , ubiquitin isopeptidase Y , ubiquitin specific protease 8 , ubiquitin thioesterase 8 , ubiquitin thiolesterase 8 , putative deubiquitinating enzyme

GENE ID SPECIES
9310109 Arabidopsis lyrata subsp. lyrata
10031598 Arthroderma gypseum CBS 118893
100408559 Callithrix jacchus
100437819 Pongo abelii
9101 Homo sapiens
296121 Rattus norvegicus
84092 Mus musculus
100157546 Sus scrofa
415451 Gallus gallus
100351436 Oryctolagus cuniculus
100720255 Cavia porcellus
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