Ubiquitin-Conjugating Enzyme E2B (UBE2B) ELISA Kits

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping UBE2B Antibodies (61) and UBE2B Proteins (20) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
UBE2B 7320 P63146
UBE2B 81816 P63149
UBE2B 22210 P63147
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Top UBE2B ELISA Kits at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
  96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days

More ELISA Kits for UBE2B Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2B (UBE2B) interaction partners

  1. RAD6 is upregulated in response to chemotherapy and significantly correlated with expression of ovarian cancer (OC) stem cell signaling genes ALDH1A1 and SOX2 and poor prognosis of OC patients.

  2. These data deepen insights into the vital role of RAD6/translesion synthesis in platinum drug tolerance and reveal clinical benefits of targeting RAD6 with SMI#9 for managing chemoresistant cancers.

  3. These results point to an important role of the affinity between RNF4 and its cognate RAD6B or UBCH5B in governing the multiplicity of substrate ubiquitination.

  4. RAD6 promotes proteasome activity and nuclear translocation by enhancing the degradation of PSMF1 and the lamin B receptor.

  5. In conclusion, we reveal that miR-455-5p expression is regulated by the TGF-beta-dependent pathway, which subsequently leads to UBE2B down-regulation and contributes to oral cancer tumourigenesis.

  6. Data show that the ubiquitin-conjugating enzyme E2 RAD6A/B-MDM2 ubiquitin ligase machinery regulates anti-silencing function 1A protein (ASF1A) degradation.

  7. These findings show the importance of Rad6 in ovarian cancer and emphasize the need for further studies of Rad6 as a potential target for the treatment of ovarian cancer.

  8. A novel variant (Chr5.133706925 A > G) residing in the UBE2B gene promoter region confers a high risk for idiopathic azoospermia in a Chinese population.

  9. RAD6 physically interacts with heterochromatin protein 1alpha and ubiquitinates HP1alpha at residue K154, thereby promoting heterochromatin protein 1alpha degradation through the autophagy pathway

  10. UBE2B mRNA alterations are associated with severe oligozoospermia in infertile men.

  11. RNF168, in complex with RAD6A or RAD6B, is activated in the DNA-damage-induced protein ubiquitination cascade.

  12. UBE2B polymorphisms g.-293T>G, g.20016A>G and g.9157A>G are not associated with male infertility, and the GA haplotype is likely a protective factor for male fertility in Northeast Chinese men.

  13. beta-catenin and Rad6B interacting regions, were identified.

  14. Hydroquinone could upregulate the expression of Rad6B in L-02 hepatic cells.

  15. The Rad6-Rad18 enzyme plays an essential role in promoting replication through DNA lesions by translesion synthesis in mammalian cells.

  16. RAD6 can form a ternary complex with MDM2 and p53 that contributes to the degradation of p53.

  17. Data show that the homodimeric Rad18 RING domain can recruit two Rad6b E2 enzymes, whereas the full-length Rad18 homodimer binds only to a single Rad6b molecule.

  18. Ubc2/Rad6 ser(120) regulates ubiquitin-dependent N-end rule targeting by E3{alpha}/Ubr1

  19. Rad6B is a fundamental component of postreplication DNA repair and can be used as an independent marker for determining response to neoadjuvant chemotherapy.

  20. MCF10A cells stably transfected with antisense RAD6B display hypersensitivity to damage-inducing drugs.

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2B (UBE2B) interaction partners

  1. Results reveal that RAD6B and RNF8 contribute to nucleosome removal during spermiogenesis.

  2. RNF168, in complex with RAD6A or RAD6B, is activated in the DNA-damage-induced protein ubiquitination cascade.

  3. These results suggest that Ube2b, as a direct androgen receptor transcriptional target in Sertoli cells, mediates the function of androgen recpetor in spermatogenesis by promoting H2A ubiquitylation.

  4. HR6B represses major satellite repeat transcription in spermatocytes, and functions in the maintenance of X chromosome silencing in spermatocytes and spermatids.

  5. The present findings reveal a specific requirement for the ubiquitin-conjugating activity of HR6B in relation to dynamic aspects of the synaptonemal complex and meiotic recombination in spermatocytes.

  6. Ube2b deficient mice are shown to present male infertility and sperm head shape anomalies.

  7. HR6B exerts control over different histone modifications in spermatocytes and spermatids, and that this function contributes to the postmeiotic maintenance of X chromosome silencing.

UBE2B Antigen Profile

Antigen Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.

Gene names and symbols associated with UBE2B

  • ubiquitin conjugating enzyme E2 B (UBE2B) antibody
  • ubiquitin-conjugating enzyme E2B (Ube2b) antibody
  • ubiquitin conjugating enzyme E2 B (ube2b) antibody
  • ubiquitin-conjugating enzyme E2B (RAD6 homolog) (ube2b) antibody
  • ubiquitin conjugating enzyme E2 B S homeolog (ube2b.S) antibody
  • 2610301N02Rik antibody
  • E2-14k antibody
  • e2-17kda antibody
  • hhr6b antibody
  • hr6b antibody
  • mHR6B antibody
  • Rad6b antibody
  • ubc2 antibody
  • zgc:100921 antibody

Protein level used designations for UBE2B

E2 protein , RAD6 homolog B , ubiquitin carrier protein B , ubiquitin-conjugating enzyme E2 B , ubiquitin-conjugating enzyme E2-17 kDa , ubiquitin-conjugating enzyme E2B (RAD6 homolog) , ubiquitin-protein ligase B , E2(14k) , ubiquitin conjugating enzyme , ubiquitin-conjugating enzyme E2(14k) , ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae) , ubiquitin-conjugating enzyme E2B, RAD6 homolog , ubiquitin-conjugating enzyme E2B, RAD6 homology , HR6B , ubiquitin conjugating-protein , Ubiquitin-conjugating enzyme E2 B , ubiquitin-conjugating enzyme E2 , E214K

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100381250 Ovis aries
22210 Mus musculus
100513527 Sus scrofa
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