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Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. Additionally we are shipping UBE2F Antibodies (61) and many more products for this protein.
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By ubiquitylating and degrading NOXA (show PMAIP1 Proteins) through activating CRL5, UBE2F selectively promotes lung cancer cell survival and could, therefore, serve as a novel cancer target
Distinct preferences of UBC12 (show ube2m Proteins) and UBE2F peptides for inhibiting different DCNLs, including the oncogenic DCNL1 (show DCUN1D1 Proteins).
Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5 (By similarity).
, NEDD8-conjugating enzyme UBE2F
, NEDD8 carrier protein UBE2F
, NEDD8 protein ligase UBE2F
, NEDD8-conjugating enzyme 2
, ubiquitin-conjugating enzyme E2 F