Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).. Additionally we are shipping UBE2O Antibodies (45) and many more products for this protein.
Showing 4 out of 5 products:
UBE2O is a self-contained quality control factor that comprises substrate recognition and ubiquitin transfer activities within a single protein to efficiently target orphans of multiprotein complexes for degradation.
UBE2O mediates c-Maf (show MAF Proteins) polyubiquitination and degradation, induces MM cell apoptosis, and suppresses myeloma tumor growth, which provides a novel insight in understanding myelomagenesis and UBE2O biology.
UBE2O specifically targets AMPKalpha2 (show PRKAA2 Proteins) for ubiquitination and degradation, and thereby promotes activation of the mTOR (show FRAP1 Proteins)-HIF1alpha (show HIF1A Proteins) pathway.
UBE2O defines an atypical ubiquitin-signaling pathway that coordinates the function of BAP1 (show RNF2 Proteins).
UBE2O negatively regulates TRAF6 (show TRAF6 Proteins)-mediated NF-kappaB (show NFKB1 Proteins) activation by inhibiting TRAF6 (show TRAF6 Proteins) polyubiquitination.
monoubiquitinated SMAD6 (show SMAD6 Proteins) impairs the binding affinity of non-modified SMAD6 (show SMAD6 Proteins) to the BMP type I receptor. Moreover, UBE2O and SMAD6 (show SMAD6 Proteins) cooperated in the regulation of BMP7 (show BMP7 Proteins)-induced adipogenesis
UBE2O recognized ribosomal proteins and other substrates directly, targeting them to proteasomes for degradation.
Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).
ubiquitin-conjugating enzyme E2O
, ubiquitin-conjugating enzyme E2 O-like
, ubiquitin carrier protein O
, ubiquitin-conjugating enzyme E2 O
, ubiquitin-conjugating enzyme E2 of 230 kDa
, ubiquitin-conjugating enzyme E2-230K
, ubiquitin-protein ligase O
, ubiquitinating enzyme E2-230 kDa