anti-Upstream Transcription Factor 2, C-Fos Interacting (USF2) Antibodies

Mouse (Murine) Upstream Transcription Factor 2, C-Fos Interacting (USF2) interaction partners

1. Pdx1, USF1 and USF2 co-ordinately regulate Alx3 gene expression in pancreatic beta-cells.

2. AGTRAP expression is regulated by USF1 and USF2

3. USF1 and USF2 are important regulatory factors for Alx3 gene expression in different cell types

4. Data suggest that both USF1 and USF2 are essential for angiotensinogen (AGT) transcriptional regulation, and distinct sex-specific and tissue-specific mechanisms are involved in the activities of these transcription factors.

5. USF-1 but not USF-2 was strongly enriched at Dbeta2 in chromatin from either Rag2-/- double-negative thymocytes or Rag2-/- thymocytes that express a rearranged Tcrb transgene.

6. USF binding to the E-box at -893/-888 serves to trans-repress basal expression and IL-1beta induction of the iNOS promoter.

7. USF1 and USF2 play a functional role in RANKL-dependent TRAP expression during osteoclast differentiation.

8. Blood oxytocin concentrations on d 9 postpartum were also lower in Usf2-/- mice than Usf2+/+ mice

9. Data show that USF1/-2 and CREB transcription factors binding to the cyclooxygenase-2 promoter induced H. pylori-dependent cox-2 transcription.

10. transcription factors upstream stimulatory factor (USF) and c-Myc may exert opposing effects on PIGR promoter activity

11. USF2 inhibited cellular transformation by preventing transcriptional repression by c-Myc.

12. Wild-type and USF2 knockout mice exhibited a 2.5-fold stimulation of renal TGF-beta1 expression upon fasting.

13. USF2 might be one of the regulators for the expression of the Runx2 gene in D1 cells.

14. Hyperglycemia stimulated USF2 expression in glomeruli from diabetic mice, associated with TSP1, TGF-beta, and fibronectin in glomeruli, leading to diabetic nephropathy. Overexpression augmented injury.

15. USF1 and USF2 bind the Fshr promoter and revealed differences between Sertoli and granulosa cells in compensatory responses to USF loss and the USF dimeric composition required for Fshr transcription

16. Glucose increases hepatic lipase expression in HepG2 cells via elevation of USF1 and USF2.

17. Results indicate that USFs 1 and 2 serve as modulators in the induction of OSCAR and RANKL-mediated osteoclastogenesis.

18. In this study they asked whether the interactions between USF1/USF2 and E-Box and Nrf1 and GC-Box in the brain of mouse are influenced by postnatal age and what link it has with reported age-related decrease in the expression of Fmr-1 gene.

19. The C allele of USF2 rs916145 is more frequent in biliary atresa. Decreased USF2 nuclear translocation might play a role in the decreased hepcidin expression in the cholestatic liver injury of the late stage of BA.

20. USF2 promotes renal renin expression and stimulates angiotensin II generation, leading to activation of the intrarenal renin-angiotensin system.

Human Upstream Transcription Factor 2, C-Fos Interacting (USF2) interaction partners

1. PLAG1 and USF2 cooperation is thus an important contributor to stem cell-specific expression of MSI2 and hematopoietic stem and progenitor cell-specific transcriptional circuitry.

2. TCF21 modulates Steroidogenic factor-1 and estrogen receptor beta expression through the recruitment of USF2 in endometriotic stromal cells.

3. USF2, and its target gene PAI-1, regulate serum-stimulated keratinocyte growth, and likely the cadence of cell cycle progression in replicatively competent cells as part of the injury repair program.

4. Increased upstream stimulatory factor in HCC is associated with heparanase expression. USF might be an important factor in regulating HPSE expression and act as a novel marker of metastatic recurrence of HCC patients

5. RNA Pol II on HIF1 or HIF2 target genes is primarily associated with HIF1alpha or HIF2alpha in a STAT3 or USF2 dependent manner

6. USF2 functionally interacts with YY1 blocking its inhibitory activity, in favor of CEBPB transactivation.

7. USF2 and hypoxia-inducible factor 2alpha (HIF2alpha) cooperatively activate HIF2 target genes during hypoxia.

8. Transcription factors upstream stimulatory factor 1 (USF-1) and USF-2 are indispensable for the transcription of RORgammaT in human lymphocytes.

9. Bone morphogenetic proteins and ID1 exerted an anti-apoptotic effect in mesangial cells by inhibition of USF2 transcriptional activity.

10. These data indicate that an E-box motif (RBE1) within the core promoter in the long terminal repeat of HIV-1 is a bona fide binding site for the RBF-2 transcription factor complex USF1, USF2, and TFII-I.

11. data established that high glucose stimulated USF2 expression in HK-2 cells, at least in part, through angiotensin II-AT1-dependent activation of CREB, which can contribute to diabetic tubulointerstitial fibrosis

12. Usf2 mediates quercetin-induced suppression of PAI-1 gene expression in human endothelial cells

13. This study demonstrated the involvement of USF1 and USF2 as molecular targets of Helicobacter pylori and the key role of DNA methylation in their regulation.

14. Ddata indicate that USF2 is one of the components of the FoxA1/androgen receptor transcriptional protein complex that contributes to the expression of androgen-regulated and prostate-specific genes.

15. Unregulated activation of STAT-5, ERK1/2 and c-Fos may contribute to the phenotypic transformation from myelodysplastic syndrome to acute leukaemia. Impaired ERK1/2 signalling pathways were activated only by GM-CSF but not by Epo.

16. requirement of carboxy ester lipase gene E-box for activation binds upstream regulatory factor 1 and 2

17. Cooperative E-box regulation of human GLI1 by TWIST and this protein

18. transfection of expression vectors containing USF-1 or USF-2 cDNAs activated CYP1A2 reporter gene activity, while a dominant-negative USF-2 expression vector blocked such activity.

19. defect in USF function may contribute to down-regulation of IGF2R expression in cancer cells.

20. These findings suggest that increased protein levels and DNA binding of USF1 and USF2 mediate the inhibitory effects of hypoxia and of Mash-2 on CYP19 gene expression in human placenta

Cow (Bovine) Upstream Transcription Factor 2, C-Fos Interacting (USF2) interaction partners

1. Depletion of the USFs by RNAi and expression of a dominant-negative USF mutant, were both associated with a significant decrease in P1.1-dependent reporter gene expression.

2. bovine upstream stimulatory factor 1 and 2 have roles regulating the prostaglandin G/H synthase-2 promoter in granulosa cells [USF1/USF2]