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UROD encodes an enzyme in the heme biosynthetic pathway. Additionally we are shipping Uroporphyrinogen Decarboxylase Antibodies (75) and Uroporphyrinogen Decarboxylase Kits (8) and many more products for this protein.
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a new mutation in the UROD gene in Egyptian patients with Hepatoerythropoietic porphyria, is reported.
a new insight in the conformational changes occurred in the mutant structures of UROD protein.
Data suggest that the traditional Chinese medicine (TCM) candidate potential three-in-one inhibitors for three drug target proteins epidermal growth factor receptor (EGFR (show EGFR Proteins)), Her2 (show ERBB2 Proteins), and uroporphyrinogen decarboxylase (UROD) against head and neck cancer.
Expression of the D306Y mutation results in an insoluble recombinant protein. G318R and K297N have little effect on the structure or activity of recombinant URO-D, but the proteins display reduced stability in vitro.
Among seventeen F-PCT patients, sixteen UROD mutations were identified.
analysis of uroporphyrinogen decarboxylase as a potential target for specific components of traditional Chinese medicine
Mutations in UROD gene is associated with familial porphyria cutanea tarda.
Hepatoerythropoietic porphyria and familial porphyria cutanea tarda G281E mutation in the uroporphyrinogen decarboxylase gene
function of Arg37 in uroporphyrinogen III decarboxylase
description of 3 siblings with hepatoerythropoietic porphyria; sequencing of the UROD gene revealed compound heterozygosity for a novel missense mutation, V166A, and a complex deletion/insertion, 645del1053ins10
This gene encodes an enzyme in the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
, protein UroD
, Uroporphyrinogen decarboxylase
, uroporphyrinogen III decarboxylase
, porphyrinogen carboxylase