MAFK Proteins

Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves.

Data Quality
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Type
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    Protein
Antigen
  • 6
Reactivity
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  • 1
  • 1
Application
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  • 2
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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6 Products
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2130442
$564.71
100 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3083551
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3123080
$5,227.64
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 30 to 35 Business Days
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1310017
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 85 % by SDS - PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN1098756
$646.15
Plus shipping costs $45.00
Delivery in 15 to 19 Business Days
ReactivityChicken
Application ELISA
Order details Cat. No. ABIN1640244
$2,348.50
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
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MAFK Protein Profile

Protein Summary

The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD\; MIM 609806) and ferrochelatase (FECH\; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.

Gene names and symbols associated with MAFK

  • MAF bZIP transcription factor K (MAFK) antibody
  • v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) (Mafk) antibody
  • MAF bZIP transcription factor K (Mafk) antibody
  • AW061068 antibody
  • NF-E2 antibody
  • Nfe2u antibody
  • P18 antibody

Protein level used designations for MAFK

basic-leucine zipper transcription factor MafK , erythroid transcription factor NF-E2 p18 subunit , nuclear factor erythroid-2, ubiquitous (p18) , transcription factor MafK , v-maf avian musculoaponeurotic fibrosarcoma oncogene family, protein K , v-maf musculoaponeurotic fibrosarcoma oncogene homolog K , nuclear factor, erythroid derived 2, ubiquitous , p18 NF-E2

GENE ID SPECIES
7975 Homo sapiens
17135 Mus musculus
395518 Gallus gallus
100735555 Cavia porcellus
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