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The protein encoded by VAPA is a type IV membrane protein. Additionally we are shipping VAPA Proteins (11) and VAPA Kits (3) and many more products for this protein.
Showing 10 out of 86 products:
Human Polyclonal VAPA Primary Antibody for WB - ABIN1881990
Furuita, Jee, Fukada, Mishima, Kojima: Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies. in The Journal of biological chemistry 2010
Show all 5 Pubmed References
Human Polyclonal VAPA Primary Antibody for IHC, IHC (p) - ABIN441268
Eyre, Fiches, Aloia, Helbig, McCartney, McErlean, Li, Aggarwal, Turville, Beard: Dynamic imaging of the hepatitis C virus NS5A protein during a productive infection. in Journal of virology 2014
Show all 3 Pubmed References
the component proteins of the machinery, OSBP (show OSBP Antibodies), VAP (show F10 Antibodies), SAC1 (show SACM1L Antibodies), and PITPNB (show PITPNB Antibodies), are all essential host factors for AiV (show ANXA4 Antibodies) replication. Importantly, the machinery is directly recruited to the RNA replication sites through previously unknown interactions of VAP (show F10 Antibodies)/OSBP (show OSBP Antibodies)/SAC1 (show SACM1L Antibodies) with the AiV (show ANXA4 Antibodies) proteins and with ACBD3 (show Acbd3 Antibodies).
VAP (show F10 Antibodies)-ACBD5 (show ACBD5 Antibodies)-mediated contact between the endoplasmic reticulum and peroxisomes mediate organelle maintenance and lipid homeostasis.
Effects of the combined absence of VAPA and VAPB (show VAPB Antibodies) in human cells were studied; cells lacking VAP (show F10 Antibodies) accumulate high levels of PI4P, actin comets, and trans-Golgi proteins on endosomes. Such defects are mimicked by downregulation of OSBP (show OSBP Antibodies), a VAP (show F10 Antibodies) interactor and PI4P transporter that participates in VAP (show F10 Antibodies)-dependent endoplasmic reticulum-endosomes tethers.
Our work revealed that VAP-A/B knockdown impaired the processing and secretion of PAUF, which is one of the cargo proteins of carriers of the trans-Golgi network to the cell surface.
The effects of sterol manipulation of HuH7 cells on complexes of established sterol-binding Oxysterol-binding protein (show OSBP Antibodies) related proteins with their endoplasmic reticulum receptor, VAMP-associated protein A (VAPA), were examined.
phosphorylation of ORP3 controls its association with VAPA. Furthermore, ORP3-VAPA complexes stimulate R-Ras signaling.
GPS2 (show GPS2 Antibodies) is required for the association of viral NS5A with VAP-A and hepatitis C virus replication.
STARD3 (show STARD3 Antibodies) or STARD3NL (show STARD3NL Antibodies) and VAP (show F10 Antibodies) form a novel molecular tether between late endosomes and the endoplasmic reticulum.
phosphorylation of CERT (show COL4A3BP Antibodies) at the FFAT motif-adjacent serine affects its affinity for VAP (show F10 Antibodies), which may regulate the inter-organelle trafficking of ceramide in response to the perturbation of cellular sphingomyelin and/or other sphingolipids
Viperin (show RSAD2 Antibodies) inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein VAP-33.
VAP-33 expression in dendritic cell sarcoma was related to vesicle transportation during antigen processing in dendritic cells.
These data suggest that VAPA could be involved in prestin's transportation inside outer hair cells (OHCs) and may facilitate the targeting of this abundant OHC protein to the plasma membrane.
Vapa regulates partitioning of Osbp (show OSBP Antibodies) between the endoplasmic retiuculum and the Golgi apparatus.
The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
33 kDa VAMP-associated protein
, VAMP-associated protein A
, vesicle-associated membrane protein-associated protein A
, synaptobrevin-associated protein of 33kDa
, 33 kDa Vamp-associated protein
, vesicle-associated membrane protein, associated protein a
, VAMP (vesicle-associated membrane protein)-associated protein A