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VENTX encodes a member of the Vent family of homeodomain proteins. Additionally we are shipping VENT Homeobox Proteins (3) and many more products for this protein.
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VENTX impairs expression of genes involved in erythroid differentiation and is highly expressed in patients with acute erythroid leukemia.
VentX induces apoptosis of cancer cells in a p53 (show TP53 Antibodies)-independent manner
Data suggest that homeobox (show Lbx1 Antibodies) transcription factor VentX may be a target to modulate Dendritic cells (DCs) functions and manage inflammatory diseases.
VentX regulates critical cell cycle regulators and Wnt downstream genes previously implicated in HSC/MPP proliferation and expansion.
Results provide mechanistic insight into the crucial roles of VentX in macrophage differentiation and proinflammatory activation and suggest that dysregulation of VentX may play a role in the pathogenesis of autoimmune diseases.
Data show that VentX is a direct transcriptional activator of p53-p21 and p16ink4a-Rb tumor suppression pathways.
these data extend our insights into the function of embryonic mesodermal factors in human postnatal hematopoiesis and indicate a role for VENTX in normal and malignant myelopoiesis.
a potential role of VentX in the clinical behavior of hematopoietic malignancies.
This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas.
VENT homeobox homolog
, VENT-like homeobox 2
, VENT-like homeobox protein 2
, hemopoietic progenitor homeobox protein VENTX2
, homeobox protein VENTX