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VENTX encodes a member of the Vent family of homeodomain proteins. Additionally we are shipping VENT Homeobox Proteins (3) and many more products for this protein.
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Findings suggest potential applications of homeobox protein VentX (VentX)-regulated tumor-associated macrophages (TAMs) in cancer immunotherapy.
VENTX impairs expression of genes involved in erythroid differentiation and is highly expressed in patients with acute erythroid leukemia.
VentX induces apoptosis of cancer cells in a p53-independent manner
Data suggest that homeobox transcription factor VentX may be a target to modulate Dendritic cells (DCs) functions and manage inflammatory diseases.
VentX regulates critical cell cycle regulators and Wnt downstream genes previously implicated in HSC/MPP proliferation and expansion.
Results provide mechanistic insight into the crucial roles of VentX in macrophage differentiation and proinflammatory activation and suggest that dysregulation of VentX may play a role in the pathogenesis of autoimmune diseases.
Data show that VentX is a direct transcriptional activator of p53-p21 and p16ink4a-Rb tumor suppression pathways.
these data extend our insights into the function of embryonic mesodermal factors in human postnatal hematopoiesis and indicate a role for VENTX in normal and malignant myelopoiesis.
a potential role of VentX in the clinical behavior of hematopoietic malignancies.
This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas.
VENT homeobox homolog
, VENT-like homeobox 2
, VENT-like homeobox protein 2
, hemopoietic progenitor homeobox protein VENTX2
, homeobox protein VENTX