Von Willebrand Factor Proteins (VWF)

The glycoprotein encoded by VWF functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. Additionally we are shipping VWF Antibodies (515) and VWF Kits (107) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
VWF 7450 P04275
VWF 116669  
VWF 22371 Q8CIZ8
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Top VWF Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
CHO Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$12,127.90
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$688.00
Details
Escherichia coli (E. coli) Wild boar His tag 100 μg Log in to see 15 to 18 Days
$784.00
Details
Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$608.00
Details
Insect cells (Sf9) Human DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$504.74
Details
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$560.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,201.00
Details
Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Log in to see 11 Days
$341.00
Details
Escherichia coli (E. coli) Dog GST tag,His tag 100 μg Log in to see 15 to 18 Days
$797.00
Details

VWF Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Rat (Rattus) ,

Mouse (Murine)

More Proteins for Von Willebrand Factor (VWF) Interaction Partners

Human Von Willebrand Factor (VWF) interaction partners

  1. PP2B-Aalpha-Munc18c (show STXBP3 Proteins) complex supports agonist-induced VWF secretion by HUVECs.

  2. Deficiency of the von Willebrand factor-cleaving protease ADAMTS13 (show ADAMTS13 Proteins) is central to the pathophysiology of thrombotic thrombocytopenic purpura. Reviewed is the evidence emerged from epidemiological studies of an inverse relationship between the plasma levels of ADAMTS13 (show ADAMTS13 Proteins) and the risk of acute coronary syndrome. [review]

  3. genetic variation of vWF V1565L polymorphism modulates ADAMTS13 (show ADAMTS13 Proteins) activity.

  4. Plasma levels of VWF antigen and activity are significantly increased with concomitant reduction in plasma ADAMTS13 (show ADAMTS13 Proteins) activity in patients with subarachnoid haemorrhage.

  5. Report a diagnostic algorithm that can reliably identify pathogenic variants of factor 8/9 and von Willebrand factor and diagnose patients with hemophilia A, hemophilia B or von Willebrand disease.

  6. analysis of an artificial botrocetin that can inhibit the VWF-GPIb interaction

  7. VWF binding to MMRN1 (show MMRN1 Proteins) was enhanced by shear exposure and ristocetin, and required VWF A1A2A3 region, specifically the A1 and A3 domains.

  8. coronary thrombi in STEMI patients resistant to fibrinolysis are characterised by higher fibrin, P-selectin (show SELP Proteins) and VWF content than lysis-sensitive thrombi

  9. We compared the classical Sanger sequencing approach and NGS to assess the value-added effect on the analysis of the mutation distribution in different types of VWD. Sixty-two different VWF mutations were identified, 27 of which had not been previously described. NGS detected 26 additional mutations, contributing to a broad overview of the mutant alleles present in each VWD type.

  10. These observations support the hypothesis that a significantly reduced ADAMTS13 (show ADAMTS13 Proteins)/VWF ratio in the coronary artery flow plays a pathogenic role in acute coronary syndromes (ACS (show PLA2G15 Proteins)) and suggest that transition from laminar to turbulent flow at sites of coronary stenosis further enhances VWF activation and deposition.

Pig (Porcine) Von Willebrand Factor (VWF) interaction partners

  1. In conclusion, endothelial vWF knockdown prevented angiotensin II-induced ET-1 (show EDN1 Proteins) upregulation through attenuation of NOX-mediated O2- production.

  2. alterations in glycosylation of vWF and other adhesion proteins associated with the targeting of the alpha1,3-Gal (show GAL Proteins)-epitope in mutant swine may have salutatory effects on the primate platelet activation observed in these xenografts.

Cow (Bovine) Von Willebrand Factor (VWF) interaction partners

  1. Hemodynamic activation of vWF and increased plasma ADAMTS-13 (show ADAMTS13 Proteins) may have contributed to reduced high-molecular-weight vWF multimers and impairment of the vWF-platelet aggregation pathway during mechanical circulatory support.

  2. both the gpIb-VWF interaction and the integrin alpha(2 (show ITGA2 Proteins))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 Proteins))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF is bound

Mouse (Murine) Von Willebrand Factor (VWF) interaction partners

  1. The low-molecular-weight heparin (LMWH) Tinzaparin inhibited Von Willebrand factor (VWF) fiber formation and vessel occlusion in tumor vessels by blocking thrombin (show F2 Proteins)-induced endothelial cells (ECs) activation and vascular endothelial growth factor-A (VEGF-A (show VEGFA Proteins))-mediated VWF release.

  2. In a laser injury-induced thrombosis model, P-selectin (show SELP Proteins) modulates thrombus propagation independently of VWF and TSP1 (show GZMA Proteins)

  3. Refrigeration-induced binding of VWF to platelets facilitates their rapid clearance by inducing GPIbalpha (show GP1BA Proteins)-mediated signaling.

  4. BLOC-2 (show HPS6 Proteins) subunit HPS6 (show HPS6 Proteins) deficiency affects the tubulation and secretion of von Willebrand factor from mouse endothelial cells

  5. A novel single-domain antibody against von Willebrand factor A1 domain that interferes with VWF-platelet interactions in vivo. By using this sdAb, show that the A1 domain is pertinent to the participation of VWF in the inflammatory response.

  6. These experiments delineate an unexpected pathway in which microbiota-triggered TLR2 signaling alters the synthesis of proadhesive VWF by the liver endothelium and favors platelet integrin-dependent thrombus growth.

  7. ADAMTS13 (show ADAMTS13 Proteins) controls vascular remodeling by modifying VWF reactivity during stroke recovery.

  8. these novel findings support the hypothesis that conformation of the VWF A domains plays a critical role in modulating macrophage-mediated clearance of VWF in vivo.

  9. results revealed localized vascular expression of FVIII (show F8 Proteins) and von Willebrand factor and identified lymphatic endothelial cell as a major cellular source of FVIII (show F8 Proteins) in extrahepatic tissues.

  10. Endothelial cell derivedVWF is the major determinant that mediates VWF-dependent ischemic stroke by promoting postischemic thrombo-inflammation.

VWF Protein Profile

Protein Summary

The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22.

Gene names and symbols associated with Von Willebrand Factor Proteins (VWF)

  • von Willebrand factor (VWF)
  • von Willebrand factor (vwf)
  • von Willebrand factor (Vwf)
  • Von Willebrand factor (Vwf)
  • 6820430P06Rik protein
  • AI551257 protein
  • B130011O06Rik protein
  • C630030D09 protein
  • F8VWF protein
  • si:ch1073-474e24.1 protein
  • VWD protein
  • VWF protein

Protein level used designations for Von Willebrand Factor Proteins (VWF)

von Willebrand factor , coagulation factor VIII VWF

GENE ID SPECIES
451773 Pan troglodytes
493760 Felis catus
570643 Danio rerio
619381 Monodelphis domestica
722019 Macaca mulatta
7450 Homo sapiens
116669 Rattus norvegicus
399544 Canis lupus familiaris
100009165 Oryctolagus cuniculus
399543 Sus scrofa
280958 Bos taurus
100732530 Cavia porcellus
419031 Gallus gallus
101110931 Ovis aries
22371 Mus musculus
Selected quality suppliers for VWF Proteins (VWF)
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