anti-Vpx Protein Antibodies

Plays a role in nuclear translocation of the viral pre- integration complex (PIC), thus is required for the virus to infect non-dividing cells.

Type
  • 12
    Primary antibodies
Antigen
  • 12
Reactivity
  • 12
Application
  • 12
Host
  • 12
Clonality
  • 12
Binding Specificity
  • 8
  • 4
  • 4
Conjugate
  • 3
  • 3
  • 3
  • 3
Isotype
  • 12
Format
  • 12
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12 Products
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6089621
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6089623
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6089625
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6089627
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6093211
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6093213
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6093215
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6093217
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6093219
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6093223
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6093225
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityVirus
Application ELISA
Order details Cat. No. ABIN6093221
$464.30
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
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Vpx Protein (VPX) Antigen Profile

Protein Summary

Plays a role in nuclear translocation of the viral pre- integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription (By similarity). {ECO:0000250}.

Gene names and symbols associated with anti-Vpx Protein (VPX) Antibodies

  • vpx protein (vpx) antibody

Protein level used designations for anti-Vpx Protein (VPX) Antibodies

Viral protein X , X ORF protein

GENE ID SPECIES
1490006 Simian immunodeficiency virus
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