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WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 Proteins (WFIKKN2)

The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. Additionally we are shipping WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 Antibodies (22) and WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
WFIKKN2 124857 Q8TEU8
Mouse WFIKKN2 WFIKKN2 278507 Q7TQN3
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Top WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Human Cells Human His tag 50 μg Log in to see 20 to 21 Days
$382.80
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
Details
CHO Cells Human Un-conjugated   25 μg Log in to see 8 to 11 Days
$328.90
Details
Hamster Human Un-conjugated   25 μg Log in to see 11 to 12 Days
$441.60
Details

WFIKKN2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, ,

More Proteins for WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 (WFIKKN2) Interaction Partners

Human WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 (WFIKKN2) interaction partners

  1. In this review, we summarize current knowledge about the WFIKKN (show WFIKKN1 Proteins) proteins and propose that they are "companion" proteins for various growth factors by providing localized and sustained presentation of TGFB (show TGFB1 Proteins) proteins to their respective receptors, thus regulating the balance between the activation of Smad (show SMAD1 Proteins) and non-Smad (show SMAD1 Proteins) pathways by TGFB (show TGFB1 Proteins).

  2. WFIKKN2 expression is significantly downregulated in human masticatory mucosa during wound healing

  3. Data suggest that myostatin (show MSTN Proteins) binding to its receptor (activin receptors type II) can be blocked by WFIKKN1 (show WFIKKN1 Proteins) but not WFIKKN2; various forms of myostatin (show MSTN Proteins) (promyostatin, myostatin (show MSTN Proteins) pro-domain, and latent/processed myostatin (show MSTN Proteins)) bind WFIKKN1 (show WFIKKN1 Proteins) but not WFIKKN2.

  4. After eccentric exercise, postmenopausal women not using hormone therapy (HT) expressed higher levels of GASP-1 (show GPRASP1 Proteins) while postmenopausal women using HT showed a significant increased expression over controls.

  5. data indicate that WFIKKN (show WFIKKN1 Proteins) proteins are antagonists of GDF8 (show MSTN Proteins) and GDF11 (show GDF11 Proteins), but in the case of TGFbeta1 (show TGFB1 Proteins), BMP2 (show BMP2 Proteins) and BMP4 (show BMP4 Proteins) they function as growth factor binding proteins

  6. Creatine supplementation in conjunction with resistance training lead to greater decreases in serum myostatin (show MSTN Proteins) (p<0.05), but had not additional effect on GASP-1 (show GPRASP1 Proteins) (p>0.05).

  7. Newly discovered WFIKKNPR gene structure and tissue distribution of gene expression is commpared with that of the WFIKKN (show WFIKKN1 Proteins) gene in adult and fetal tissues and organs

  8. Both WFIKKN1 (show WFIKKN1 Proteins) and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.

Mouse (Murine) WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 (WFIKKN2) interaction partners

  1. Taken together, this study provides evidence that GASP1 (show GPRASP1 Proteins) regulates CB1 (show CNR1 Proteins) receptor downregulation in vivo, and that postendocytic receptor trafficking has a key role in the development of tolerance to WIN55,212-2.

  2. Report of the identification of growth and differentiation factor-associated serum protein-1 (GASP-1) associated with endogenous myostatin (show MSTN Proteins) in normal serum

WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 (WFIKKN2) Protein Profile

Protein Summary

The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases.

Gene names and symbols associated with WFIKKN2

  • WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 (WFIKKN2)
  • WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 (Wfikkn2)
  • 2610304F08Rik protein
  • AY100450 protein
  • GASP-1 protein
  • Gasp1 protein
  • hGASP-1 protein
  • WFDC20B protein
  • WFIKKNRP protein

Protein level used designations for WFIKKN2

WAP four-disulfide core domain 20B , WAP, FS, Ig, two KU and NTR module related protein , WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 , WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein , WFIKKN-related protein , growth and differentiation factor-associated serum protein 1 , multivalent protease inhibitor protein , GASP-1 , mGASP-1

GENE ID SPECIES
124857 Homo sapiens
278507 Mus musculus
531979 Bos taurus
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