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WDR13 encodes a member of the WD repeat protein family. Additionally we are shipping WDR13 Antibodies (15) and and many more products for this protein.
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Results provide evidence that WDR13 is a novel transcriptional activator of AP1 (show JUN Proteins) target genes in the presence of JNK (show MAPK8 Proteins) signal. The lack of Wdr13 gene conferred protection to a large extent against colitis-induced colorectal tumor in mice through reduced expression of AP1 (show JUN Proteins) target genes.
Using two types of heterozygous females carrying either maternally and paternally derived mutant Wdr13 allele we provide genetic evidence that development of placenta determines body weight of mice for the entire life.
WDR13 is a novel negative regulator of the pancreatic beta cell proliferation.
WDR13 is localized to the locus XA1.1 and is predominantly expressed in the testis.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is widely expressed in various tissues. Multiple alternatively spliced transcript variants have been described for this gene.
WD repeat domain 13
, WD repeat-containing protein 13
, WD repeat domain 13 protein
, WD repeat protein 13
, memory-related protein
, WD family protein WDR13