WD Repeat Domain 83 Proteins (wdr83)

wdr83 encodes a member of the WD-40 protein family. Additionally we are shipping WD Repeat Domain 83 Antibodies (70) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
wdr83 84292 Q9BRX9
wdr83 288924 Q5BLX8
Mouse wdr83 wdr83 67836 Q9DAJ4
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Top WD Repeat Domain 83 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days

wdr83 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

More Proteins for WD Repeat Domain 83 (wdr83) Interaction Partners

Human WD Repeat Domain 83 (wdr83) interaction partners

  1. Morg1 facilitates Par6 (show PARD6A Proteins)-aPKC binding to Crb3 (show CRB3 Proteins) for definition of apical identity of epithelial cells.

  2. WDR83 and DHPS (show DHPS Proteins) were capable of forming an RNA duplex at overlapping 3' untranslated regions and this duplex increased their mutual stability, which was required for the bidirectional regulation.

  3. Component of a modular scaffold system that participates in the regulation of agonist-specific ERK (show EPHB2 Proteins) signaling.

  4. Morg1 expression is reduced in human brain tissue with ischemic damage. Reactive astrocytes in the surrounding brain tissue showed strong Morg1 expression.

Mouse (Murine) WD Repeat Domain 83 (wdr83) interaction partners

  1. High MORG1 expression is associated with diabetic nephropathy.

  2. this study shows for the first time in various renal cells that ANG II (show AGT Proteins) modulates Morg1 expression and HIF-1alpha (show HIF1A Proteins) transcriptional activity via cell type-specific mechanisms, demonstrating a novel mechanism by which ANG II (show AGT Proteins) may contribute to renal disease.

  3. The major finding of this study is that Morg1+/- mice are partially protected from cerebral ischemia and reperfusion injury in comparison to the WT (Morg1+/+) animals

  4. Morg1 may be a novel therapeutic target to limit renal injury after ischemia-reperfusion

WD Repeat Domain 83 (wdr83) Protein Profile

Protein Summary

This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with WD Repeat Domain 83 Proteins (wdr83)

  • WD repeat domain 83 (WDR83)
  • WD repeat domain 83 (Wdr83)
  • WD repeat domain 83 L homeolog (wdr83.L)
  • WD repeat domain containing 83 (Wdr83)
  • 1500041N16Rik protein
  • morg1 protein
  • RGD1306947 protein

Protein level used designations for WD Repeat Domain 83 Proteins (wdr83)

MAPK organizer 1 , WD repeat domain-containing protein 83 , mitogen-activated protein kinase organizer 1 , WD repeat protein Morg1 , MAPK cascade scaffold protein

84292 Homo sapiens
288924 Rattus norvegicus
734767 Xenopus laevis
67836 Mus musculus
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