WDYHV1 Proteins
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation.
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WDYHV Motif Containing 1 (WDYHV1) (AA 1-205) protein (His tag) Protein
WDYHV Motif Containing 1 (WDYHV1) (AA 1-209) protein (His tag) Protein
WDYHV Motif Containing 1 (WDYHV1) protein (Myc-DYKDDDDK Tag) Protein
WDYHV Motif Containing 1 (WDYHV1) (AA 1-205) protein (GST tag) Protein
WDYHV Motif Containing 1 (WDYHV1) (AA 1-202) protein (His tag) Protein
WDYHV Motif Containing 1 (WDYHV1) (AA 1-207) protein (His tag) Protein
WDYHV Motif Containing 1 (WDYHV1) (AA 1-207) protein (His tag) Protein
WDYHV1 Protein Profile
Protein Summary
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N- terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C- terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine (By similarity).
Gene names and symbols associated with WDYHV1
- WDYHV motif containing 1 (WDYHV1) antibody
- WDYHV motif containing 1 S homeolog (wdyhv1.S) antibody
- WDYHV motif containing 1 (wdyhv1) antibody
- WDYHV motif containing 1 (Wdyhv1) antibody
- 2410187C16Rik antibody
- AU014961 antibody
- AW550036 antibody
- C8orf32 antibody
- C14H8orf32 antibody
- Ntaq1 antibody
- RGD1311362 antibody
- si:rp71-45k5.3 antibody
Protein level used designations for WDYHV1
WDYHV motif containing 1 , protein N-terminal glutamine amidohydrolase , nt(Q)-amidase , N-terminal Gln amidase , WDYHV motif-containing protein 1 , protein NH2-terminal glutamine deamidase
GENE ID | SPECIES |
---|---|
464370 | Pan troglodytes |
496074 | Xenopus laevis |
609297 | Canis lupus familiaris |
704686 | Macaca mulatta |
100379822 | Xenopus (Silurana) tropicalis |
55093 | Homo sapiens |
76773 | Mus musculus |
362914 | Rattus norvegicus |
510463 | Bos taurus |
560935 | Danio rerio |
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