anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) Antibodies

WNK1 encodes a member of the WNK subfamily of serine/threonine protein kinases.

list all antibodies Gene Name GeneID UniProt
Anti-Human WNK1 WNK1 65125 Q9H4A3
Anti-Mouse WNK1 WNK1 232341 P83741
Anti-Rat WNK1 WNK1 116477 Q9JIH7
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-WNK1 Antibodies at antibodies-online.com

Showing 10 out of 178 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: WNK1 Antibody [ABIN153167] - Detection of the short form of WNK1 in F-11 cell lysate. 0.1 mL Log in to see 7 to 9 Days
$415.44
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of WNK1 expression in rat testis extract ( Lane 1). WNK1 at 250KD was detected using rabbit anti- WNK1 Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). WNK1 was detected in paraffin-embedded sections of human intestinal cancer tissues using rabbit anti-WNK1 Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. The immunohistochemical section was developed using SABC method (Catalog # SA1022). 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from 293 cells, treated with EGF 200ng/ml 30', using WNK1 (Ab-58) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using WNK1 (Ab-58) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from 293 cells treated with EGF 200ng/ml 30', using WNK1 (Phospho-Thr58) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using WNK1 (Phospho-Thr58) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Bat Rabbit Un-conjugated IHC, IHC (p) Anti-WNK1 antibody  ABIN1049464 IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Bat Rabbit Un-conjugated ELISA, IHC, IHC (p) Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with WNK1 antibody ABIN213554 at 4 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Human Testis (formalin-fixed, paraffin-embedded) stained with WNK1 antibody ABIN213556 at 7 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated IP, WB 0.1 mL Log in to see 7 to 9 Days
$556.31
Details
Human Rabbit Un-conjugated IP, WB 0.1 mL Log in to see 7 to 9 Days
$556.31
Details

Top referenced anti-WNK1 Antibodies

  1. Human Polyclonal WNK1 Primary Antibody for ICC, IF - ABIN153167 : Wade, Fang, Liu, Li, Yang, Subramanya, Maouyo, Mason, Ellison, Welling: WNK1 kinase isoform switch regulates renal potassium excretion. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 3 Pubmed References

  2. Polyclonal WNK1 Primary Antibody for WB - ABIN540241 : Xu, Lee, Min, Lenertz, Heise, Stippec, Goldsmith, Cobb: WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension. in Cell research 2005 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal WNK1 Primary Antibody for IHC (p) - ABIN2477141 : Lyn, Ayoub, Saunders, Dische: Chest radiography or computed tomography to assess the response of lung cancer to radiotherapy. in Clinical oncology (Royal College of Radiologists (Great Britain)) 1992 (PubMed)
    Show all 2 Pubmed References

More Antibodies against WNK1 Interaction Partners

Human WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. A new WNK1/HSN2 founder mutation has been found in Japanese patients with hereditary sensory and autonomic neuropathy.

  2. Small interfering RNA knockdown of MAPK7 (show MAPK7 Antibodies) demonstrated that MAPK7 (show MAPK7 Antibodies) regulates a subset of WNK1-regulated genes and controls the migration and cell proliferation

  3. The AA genotype of WNK1 rs1468326 is related with an increased risk for preeclampsia.

  4. Mutated WNK1 is a driver of chronic lymphocytic leukemia.

  5. Using small-interfering RNA-mediated WNK1 knockdown, we show autophagosome formation and autophagic flux are accelerated. In cells with reduced WNK1, basal and starvation-induced autophagy is increased. We also show that depletion of WNK1 stimulates focal class III phosphatidylinositol 3-kinase complex (PI3KC3) activity, which is required to induce autophagy.

  6. WNK1 and the associated phosphorylation of the PCF11 (show PCF11 Antibodies) CID (show CENPA Antibodies) act to promote transcript release from chromatin-associated Pol II (show 0 Antibodies), which in turn facilitates mRNA export to the cytoplasm

  7. Akt3 (show AKT3 Antibodies) constitutively suppresses macropinocytosis in macrophages through a novel WNK1/SGK1 (show SGK1 Antibodies)/Cdc42 (show CDC42 Antibodies) pathway.

  8. NKCC1 (show SLC12A2 Antibodies) and KCCs are coordinately regulated by L-WNK1 isoforms.

  9. Single nucleotide polymorphisms STK39 (show STK39 Antibodies) and WNK were associated with hypertension and BP in our multicenter Belgian case-control study

  10. these data provide insight into the mechanism regulating Cl(-) homeostasis in immature neurons, and suggest that WNK1-regulated changes in KCC2 (show SLC12A5 Antibodies) phosphorylation contribute to the developmental excitatory-to-inhibitory GABA sequence.

Pig (Porcine) WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. HSN2 is a nervous system-specific exon of the WNK1 gene (WNK1/HSN2 isoform).

Chimpanzee WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. HSN2 is a nervous system-specific exon of the WNK1 gene (WNK1/HSN2 isoform).

Rhesus Monkey WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. HSN2 is a nervous system-specific exon of the WNK1 gene (WNK1/HSN2 isoform).

Xenopus laevis WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. HSN2 is a nervous system-specific exon of the WNK1 gene (WNK1/HSN2 isoform).

Horse (Equine) WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. HSN2 is a nervous system-specific exon of the WNK1 gene (WNK1/HSN2 isoform).

Mouse (Murine) WNK Lysine Deficient Protein Kinase 1 (WNK1) interaction partners

  1. The differential regulation of ROMK (show KCNJ1 Antibodies), large-conductance Ca(2 (show CA2 Antibodies)+)-activated K(+) (BK) channel (show KCNMA1 Antibodies), BK-alpha and NKCC2 (show SLC12A1 Antibodies) between female and male mice, at least, were partly mediated via WNK1 pathway, which may contribute to the sexual dimorphism of plasma K(+) and blood pressure control.

  2. this study identified the WNK1 kinase as a regulator of both integrin-mediated adhesion and T cell migration

  3. Akt3 (show AKT3 Antibodies) constitutively suppresses macropinocytosis in macrophages through a novel WNK1/SGK1 (show SGK1 Antibodies)/Cdc42 (show CDC42 Antibodies) pathway.

  4. Electrophysiological analysis showed that WNK1/HSN2 shifted the concentration of Cl(-)such that GABA signaling resulted in a less hyperpolarized state (increased neuronal activity) rather than a more hyperpolarized state (decreased neuronal activity) in mouse spinal nerves.

  5. A high-K(+) diet induced an increase in L-WNK1 expression selectively in intercalated cells and may contribute to enhanced BK channel (show KCNMA1 Antibodies) expression and K(+) secretion in collecting ducts.

  6. these data provide insight into the mechanism regulating Cl(-) homeostasis in immature neurons, and suggest that WNK1-regulated changes in KCC2 (show SLC12A5 Antibodies) phosphorylation contribute to the developmental excitatory-to-inhibitory GABA sequence.

  7. findings indicate that the proline-rich exons are modular cassettes that convert WNK1 into a NEDD4-2 (show NEDD4L Antibodies) substrate, thereby linking aldosterone and other NEDD4-2 (show NEDD4L Antibodies)-suppressing antinatriuretic hormones to NCC (show SLC12A3 Antibodies) phosphorylation status.

  8. enhances BK channel function by reducing ERK1/2 signaling-mediated lysosomal degradation of the channel

  9. increased protein expression levels of WNK1 and WNK4 (show WNK4 Antibodies) kinases cause PHAII by KLHL3 (show KLHL3 Antibodies) R528H mutation due to impaired KLHL3 (show KLHL3 Antibodies)-Cullin3-mediated ubiquitination.

  10. study identifies a separation of functions for the WNK1-activated protein kinases OSR1 (show OSR1 Antibodies) and SPAK (show STK39 Antibodies) in mediating proliferation, invasion, and gene expression in endothelial cells

WNK1 Antigen Profile

Protein Summary

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.

Gene names and symbols associated with WNK1

  • WNK lysine deficient protein kinase 1 (WNK1) antibody
  • WNK lysine deficient protein kinase 1 L homeolog (wnk1.L) antibody
  • WNK lysine deficient protein kinase 1 (wnk1) antibody
  • serine/threonine-protein kinase WNK1 (LOC100056745) antibody
  • WNK lysine deficient protein kinase 1 (Wnk1) antibody
  • with no lysine (K) kinase 1 (WNK1) antibody
  • 6430573H23Rik antibody
  • ATWNK1 antibody
  • EG406236 antibody
  • hsan2 antibody
  • Hsn2 antibody
  • kdp antibody
  • mKIAA0344 antibody
  • p65 antibody
  • pha2c antibody
  • Prkwnk1 antibody
  • psk antibody
  • T9J14.14 antibody
  • T9J14_14 antibody
  • with no lysine (K) kinase 1 antibody
  • WNK1 antibody
  • ZIK4 antibody

Protein level used designations for WNK1

WNK lysine deficient protein kinase 1 isoform , erythrocyte 65 kDa protein , prostate-derived sterile 20-like kinase , protein kinase with no lysine 1 , serine/threonine-protein kinase WNK1 , WNK lysine deficient protein kinase 1 , serine/threonine-protein kinase WNK1-like , protein kinase lysine-deficient 1

GENE ID SPECIES
65125 Homo sapiens
406235 Sus scrofa
427925 Gallus gallus
451739 Pan troglodytes
477728 Canis lupus familiaris
506433 Bos taurus
706493 Macaca mulatta
734160 Xenopus laevis
100017207 Monodelphis domestica
100036683 Xenopus (Silurana) tropicalis
100056745 Equus caballus
100350906 Oryctolagus cuniculus
100436057 Pongo abelii
100594288 Nomascus leucogenys
232341 Mus musculus
116477 Rattus norvegicus
819651 Arabidopsis thaliana
100729855 Cavia porcellus
Did you look for something else?