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The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. Additionally we are shipping WBP2 Proteins (8) and and many more products for this protein.
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Human Monoclonal WBP2 Primary Antibody for IF, ELISA - ABIN525255
Chan, Lim, Huang, Chong, Gunaratne, Hogue, Blackstock, Harvey, Hong: WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ. in Oncogene 2011
Show all 2 Pubmed References
WBP2/ITCH signaling functions to link the intricate Wnt (show WNT2 Antibodies) and Hippo signaling networks in breast cancer.
the miR (show MLXIP Antibodies)-206/WBP2 axis can modulate tamoxifen sensitivity via regulating G1/S progression in estrogen receptor (show ESR1 Antibodies) + breast cancer
The authors reported that the loss of Wbp2 expression leads to progressive high-frequency hearing loss in mouse, as well as in two deaf children, each carrying two different variants in the WBP2 gene.
data indicate that WBP-2 enhances ER transactivation function at certain genes by facilitating the recruitment and/or the stabilization of a histone modifier enzyme that favors a relaxed chromatin structure, permissive of transcription
The WW1 and WW2 domains of YAP2 (show YAP1 Antibodies) recognize various PPXY motifs within WBP2 and WBP1 (show DDOST Antibodies) in a highly promiscuous and subtle manner.
Data show that direct interaction of Wbp2 with TAZ (show TAZ Antibodies) depends on the WW domain (show DRP2 Antibodies) of TAZ (show TAZ Antibodies).
WW domain binding protein-2, an E6-associated protein interacting protein, acts together with YAP (show YAP1 Antibodies) as coactivators of estrogen and progesterone receptors.
This study established WBP2 as a tyrosine phosphorylation target of estrogen signaling via EGFR (show EGFR Antibodies) crosstalk.
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined.
WW domain-binding protein 2
, WW domain binding protein 2
, WW domain binding protein 2-like