Werner Helicase Interacting Protein 1 (WRNIP1) ELISA Kits

Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). Additionally we are shipping WRNIP1 Antibodies (77) and WRNIP1 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
WRNIP1 56897 Q96S55
WRNIP1 78903 Q91XU0
WRNIP1 282835 Q8CG07
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Top WRNIP1 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat
  96 Tests Log in to see 15 to 18 Days
$875.60
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Human
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$875.60
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Mouse
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$875.60
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More ELISA Kits for WRNIP1 Interaction Partners

Human Werner Helicase Interacting Protein 1 (WRNIP1) interaction partners

  1. findings define the WHIP-TRIM14-PPP6C mitochondrial signalosome required for RIG-I (show DDX58 ELISA Kits)-mediated innate antiviral immunity.

  2. WRNIP1 connects PCNA (show PCNA ELISA Kits) monoubiquitination with ATMIN/ATM (show ATM ELISA Kits) to activate ATM (show ATM ELISA Kits) signalling in response to replication stress and contribute to the maintenance of genomic stability.

  3. The authors show that WRNIP1 is directly involved in preventing uncontrolled MRE11 (show MRE11A ELISA Kits)-mediated degradation of stalled replication forks by promoting RAD51 (show RAD51 ELISA Kits) stabilization on ssDNA.

  4. We propose that UBZ domains can be divided into at least two different types in terms of the ubiquitin-binding surfaces: the pol type and the WRNIP1 type

  5. results suggest that WRNIP1 functions upstream of Poleta in the response to UV irradiation

  6. Mutated WRNIP1 with a deleted ATPase (show DNAH8 ELISA Kits) domain or with mutations in lysine residues accumulated in laser light irradiated sites, suggesting that the ATPase (show DNAH8 ELISA Kits) domain of WRNIP1 and ubiquitination of WRNIP1 are dispensable for the accumulation.

  7. WHIP was identified as a partner/component of the nuclear envelope/nuclear pore complex (NPC (show NPC1 ELISA Kits)) and set forth to investigate a role for the protein positioned at the NPC (show NPC1 ELISA Kits).

  8. These results indicate that WRNIP1 functions as a modulator for initiation or restart events during pol delta (show POLD1 ELISA Kits)-mediated DNA synthesis and that its ATPase (show DNAH8 ELISA Kits) activity is utilized to sense DNA ends and to regulate the extent of stimulation.

  9. Werner helicase-interacting protein 1 binds polyubiquitin (show UBB ELISA Kits) via its zinc finger domain

  10. analysis of the composite and regulated topography of Wrnip1 in the human nucleus highlights its potential role in replication and other nuclear transactions

Mouse (Murine) Werner Helicase Interacting Protein 1 (WRNIP1) interaction partners

  1. Mutations in the Walker A motifs of the two proteins revealed that WRNIP1, but not WRN, must bind ATP before an efficient interaction can occur.

WRNIP1 Antigen Profile

Antigen Summary

Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene.

Gene names and symbols associated with WRNIP1

  • Werner helicase interacting protein 1 (WRNIP1) antibody
  • Werner helicase interacting protein 1 L homeolog (wrnip1.L) antibody
  • Werner helicase interacting protein 1 (wrnip1) antibody
  • ATPase WRNIP1 (EDI_075920) antibody
  • ATPase WRNIP1 (CpipJ_CPIJ017857) antibody
  • ATPase WRNIP1 (PITG_07216) antibody
  • ATPase WRNIP1 (VDBG_02914) antibody
  • Werner helicase interacting protein 1 (Wrnip1) antibody
  • ATPase WRNIP1 (PGTG_08805) antibody
  • 4833444L21Rik antibody
  • bA420G6.2 antibody
  • RP11-420G6.2 antibody
  • Whip antibody
  • Wrnip antibody
  • wrnip1 antibody
  • zgc:85976 antibody

Protein level used designations for WRNIP1

ATPase WRNIP1 , Werner helicase interacting protein 1 , Werner helicase-interacting protein 1 , putative helicase RUVBL , Werner helicasae interacting protein 1 , Werner syndrome homolog interacting protein , werner helicase-interacting protein 1

GENE ID SPECIES
788824 Bos taurus
462392 Pan troglodytes
707250 Macaca mulatta
734231 Xenopus laevis
56897 Homo sapiens
405856 Danio rerio
5882536 Entamoeba dispar SAW760
6052914 Culex quinquefasciatus
9471556 Phytophthora infestans T30-4
9532917 Verticillium alfalfae VaMs.102
78903 Mus musculus
282835 Rattus norvegicus
395089 Gallus gallus
100158593 Xenopus (Silurana) tropicalis
10529992 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100595079 Nomascus leucogenys
100155921 Sus scrofa
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