Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) Proteins

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton.

Data Quality
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Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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7 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3075435
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
ReactivityHuman
Application AA, AP, ELISA, WB
Order details Cat. No. ABIN1325154
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 90 %
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN4988928
$640.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 90 %
ReactivityRat (Rattus)
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN4988929
$656.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN6019801
$661.28
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityRat (Rattus)
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN6019803
$661.28
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2735483
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
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Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) Protein Profile

Protein Summary

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.

Gene names and symbols associated with WAS

  • Wiskott-Aldrich syndrome (WAS) antibody
  • neural Wiskott-Aldrich syndrome protein (LOC5578888) antibody
  • wiskott-aldrich syndrome protein (CpipJ_CPIJ006699) antibody
  • Wiskott-Aldrich syndrome (Was) antibody
  • Wiskott-Aldrich syndrome L homeolog (was.L) antibody
  • Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b (wasb) antibody
  • imd2 antibody
  • SCNX antibody
  • thc antibody
  • thc1 antibody
  • U42471 antibody
  • was antibody
  • wasp antibody
  • wu:fk81c08 antibody
  • zgc:64164 antibody

Protein level used designations for WAS

eczema-thrombocytopenia , thrombocytopenia 1 (X-linked) , wiskott-Aldrich syndrome protein , wiskott-aldrich syndrome protein , Wiskott-Aldrich syndrome homolog , wiskott-Aldrich syndrome protein homolog , Wiskott-Aldrich syndrome (eczema-thrombocytopenia) , Wiskott-Aldrich syndrome L homeolog , wiskott-Aldrich syndrome L homeolog , wasp1

GENE ID SPECIES
7454 Homo sapiens
5578888 Aedes aegypti
6038460 Culex quinquefasciatus
22376 Mus musculus
317371 Rattus norvegicus
100037214 Xenopus laevis
335158 Danio rerio
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