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WHSC1 encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. Additionally we are shipping WHSC1 Antibodies (50) and many more products for this protein.
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This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4\;14)(p16.3\;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
Wolf-Hirschhorn syndrome candidate 1 protein
, Wolf-Hirschhorn syndrome candidate 1
, probable histone-lysine N-methyltransferase NSD2
, IL5 promoter REII region-binding protein
, histone-lysine N-methyltransferase NSD2
, multiple myeloma SET domain containing protein type III
, nuclear SET domain-containing protein 2
, trithorax/ash1-related protein 5
, multiple myeloma SET domain-containing protein
, wolf-Hirschhorn syndrome candidate 1 protein homolog