YTHDF2 Proteins
YTHDF2 encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain.
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YTH Domain Family, Member 2 (YTHDF2) (AA 2-579) protein (His tag) Protein
YTH Domain Family, Member 2 (YTHDF2) (AA 1-579) protein (GST tag) Protein
YTHDF2 Protein Profile
Protein Summary
This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Gene names and symbols associated with YTHDF2
- YTH N(6)-methyladenosine RNA binding protein 2 L homeolog (ythdf2.L) antibody
- YTH N6-methyladenosine RNA binding protein 2 (YTHDF2) antibody
- HGRG8 antibody
- MGC82537 antibody
- NY-REN-2 antibody
Protein level used designations for YTHDF2
YTH domain family, member 2 , YTH domain family 2 , high glucose-regulated protein 8 , 9430020E02Rik , CLL-associated antigen KW-14 , YTH domain family protein 2 , high-glucose-regulated protein 8 , renal carcinoma antigen NY-REN-2
| GENE ID | SPECIES |
|---|---|
| 447009 | Xenopus laevis |
| 740305 | Pan troglodytes |
| 51441 | Homo sapiens |
| 541050 | Bos taurus |
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