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ZIC4 encodes a member of the ZIC family of C2H2-type zinc finger proteins. Additionally we are shipping ZIC4 Antibodies (93) and and many more products for this protein.
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The rate of methylation of ZIC1, ZIC4, HHIP, and DACT2 in tumors was very high, while methylation of CXXC4 was low to moderate in OSCC and LSCC.
ZIC4 CPG island methylation predicts progression in bladder cancer.
Dandy-Walker malformation associated with heterozygous ZIC1 and ZIC4 deletion.
Through physical mapping of 3q2 interstitial deletions in several individuals with Dandy-Walker malformation (DWM), we defined the first critical region associated with DWM, encompassing two adjacent Zinc finger in cerebellum genes, ZIC1 and ZIC4.
Zic4 expression was detected mainly in the neural plate border, dorsal neural tube, and somites, and was similar to that of Zic1, which is adjacent to Zic4 on the same chromosome.
Zic1 and Zic4 have both Shh-dependent and -independent roles during cerebellar development and multiple developmental disruptions underlie Zic1/4-related Dandy-walker malformation.
Results describe the molecular properties of Zic4 and Zic5 proteins.
Zic4 has an expression pattern distinct from, but partly overlapping with, other members of the Zic gene family
These findings identify roles for two differentially expressed genes, Zic4 and Foxp2, in the development of the principal auditory relay nucleus, the medial geniculate nucleus, and principal visual relay nucleus, the lateral geniculate nucleus
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene.
zinc family member 4 protein HZIC4
, zinc finger protein ZIC 4
, zinc finger protein of the cerebellum 4
, Zinc finger protein of the cerebellum 4
, Zic family member 4 (odd-paired homolog, Drosophila)