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ZDHHC9 encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. Additionally we are shipping Zinc Finger, DHHC-Type Containing 9 Antibodies (42) and many more products for this protein.
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studies suggest that ZDHHC9 may serve as a safe and effective target for developing therapies against NRAS (show NRAS Proteins)-driven cancers
Data demonstrate that ZDHHC9 mutations are associated with reductions in cortical thickness and white matter microstructural integrity, particularly in regions and networks known to contribute to language function.
De novo ZDHHC9 mutation was identified in a patient with X-linked intellectual disability.
Report demonstrated that MMSA-1 is specifically expressed in multiple myeloma patients and its upregulation is associated with unfavorable clinical features and poor prognosis.
ZDHHC9 gene mutation is associated with Lujan-Fryns syndrome.
Two missense mutation, R148W and P150S,of zDHHC9, affecting the autopalmitoylation is associated with the X-linked intellectual disability.
Data indicate that sp-Erf2/zDHHC9 palmitoylates Ras proteins in a highly selective manner in the trans-Golgi compartment to facilitate PM targeting via the trans-Golgi network, a role that is most certainly critical for Ras-driven tumorigenesis.
MMSA-1 may play a pivotal role in multiple myeloma proliferation and osteolysis destruction.
Studies indicate that mutations in DHHC9 were associated with X-linked mental retardation.
Data show that H- and N-Ras (show NRAS Proteins) are palmitoylated by a human protein palmitoyltransferase encoded by the ZDHHC9 and GCP16 (show GOLGA7 Proteins) genes.
This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.
zinc finger, DHHC-type containing 9
, zinc finger, DHHC domain containing 9
, palmitoyltransferase ZDHHC9
, zinc finger DHHC domain-containing protein 9
, palmitoyltransferase ZDHHC9-like
, Asp-His-His-Cys domain containing protein 9
, antigen MMSA-1
, zinc finger protein 379
, zinc finger protein 380
, zinc finger, DHHC domain containing 10
, membrane-associated DHHC9 zinc finger protein