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Transcriptional activator. Additionally we are shipping Zinc Finger Protein 143 Antibodies (25) and and many more products for this protein.
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The inhibition of ZNF143 activity by small molecules induced tumor regression.
Data show that zinc finger protein 143 (ZNF143) promotes epithelial-mesenchymal transition (EMT (show ITK Proteins)) through regulating PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) pathway in gastric cancer (GC) cells.
The results show that as an important partner of CTCF, ZNF143 helps establishing the conserved chromatin structure by cooperating with cohesin.
ZNF143 is directly recruited to the promoter of genes engage in chromatin interactions, where it binds to its DNA recognition sequence.
THAP11, ZNF143, and HCF-1 (show HCFC1 Proteins) form a mutually dependent complex on chromatin, which is independent of E2F (show E2F1 Proteins) occupancy.
ZNF143 expresses different 3'-untranslated regions (3'-UTR) as a result of alternative polyadenylation
High zinc-finger protein 143 is associated with cancer cell migration and invasion through ZEB1 and E-cadherin (show CDH1 Proteins) in colon cancer.
HCFC1 (show HCFC1 Proteins) is a common component of active human CpG-island promoters and coincides with ZNF143, THAP11, YY1 (show YY1 Proteins), and GABP transcription factor occupancy.
ZNF143 upregulated GPX1 (show GPX1 Proteins) activity and protecting cells from oxidative damage.
GIPC (show GIPC1 Proteins) is involved in IGF-1 (show IGF1 Proteins) signaling leading to ZNF143 expression through the regulation of ROS (show ROS1 Proteins) production, which may play a role for colon cancer tumorigenesis.
Zfp143 regulates Nanog (show NANOG Proteins) expression through modulation of Oct4 (show POU5F1 Proteins) binding.
STAF influences selenoprotein expression by enhancing Sec tRNA gene synthesis in an organ-specific manner
The knockdown of the transcriptional activator ZNF143 by injection of translational-blocking Morpholino Oligonucleotides causes many significant phenotypic effects in zebrafish embryos
Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8 (By similarity).
, selenocysteine tRNA gene transcription-activating factor
, transcriptional activator Staf
, selenocysteine tRNA gene transcription activating factor
, zinc finger protein 80, related sequence 1
, Selenocysteine tRNA gene transcription-activating factor
, selenocysteine tRNA activating factor
, zinc finger protein 143