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Transcription factor required for myelination of differentiated oligodendrocytes. Additionally we are shipping Zinc Finger Protein 24 Antibodies (67) and Zinc Finger Protein 24 Kits (2) and many more products for this protein.
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miR-940 promoted gastric cancer progression by directly downregulating ZNF24 expression.
In vivo, knockdown of ZNF24 specifically in microvascular endothelial cells led to significantly decreased formation of functional vascular networks.
results suggest that consecutive ZF1-2 is critical for the regulation of ZNF24 nuclear localization and its transactivation function.
ZNF24 represses VEGF transcription through direct binding to an 11-bp fragment of the VEGF proximal promoter and that it functions as a negative regulator of tumor growth by inhibiting angiogenesis.
ZNF24 may be implicated in transcriptional regulation of genes associated with oncogenesis via interaction with H2A.Z.
ZNF191 can directly bind to the CTNNB1 promoter and activate the expression of beta-catenin and its downstream target genes such as cyclin D1 in hepatoma cell lines.
These data suggest that ZNF24 is involved in negative regulation of PDGFR-beta and may represent a novel repressor of PDGFR-beta transcription.
Overexpression and purification of single zinc finger peptides of ZNF191 were performed.
ZNF191 is a pleiotropic factor that has a role in hematopoiesis, brain development, and tumor growth.
Data confirm ZNF191 as an essential factor acting for the promotion of the cell cycle and thus maintenance in the progenitor stage.
Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically bind to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro.
hypomyelinated CNS protein
, zinc finger ZF-12
, zinc finger protein 24
, zinc finger protein ZF-12
, lacks zinc finger domain
, retinoic acid suppression protein A
, zinc finger and SCAN domain-containing protein 3
, zinc finger protein 191
, zinc finger protein 24 (KOX 17)
, zinc finger protein KOX17