Zinc Finger Protein 278 Proteins

The protein encoded by ZNF278 contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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Application
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Host
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  • 1
Binding Specificity
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Conjugate
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Protein Type
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Format
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5 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3085597
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2735981
$302.50
50 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2735982
$302.50
50 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Wheat germ (Source)
ISO
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1314057
$338.33
2 μg
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Wheat germ (Source)
ISO
ReactivityHuman
Application AP, AA, ELISA, WB
Order details Cat. No. ABIN1314058
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
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Zinc Finger Protein 278 (ZNF278) Protein Profile

Protein Summary

The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated t1\;22p36.1\;q12. The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.

Gene names and symbols associated with ZNF278

  • POZ/BTB and AT hook containing zinc finger 1 (PATZ1) antibody
  • POZ/BTB and AT hook containing zinc finger 1 S homeolog (patz1.S) antibody
  • POZ (BTB) and AT hook containing zinc finger 1 (Patz1) antibody
  • POZ-, AT hook-, and zinc finger-containing protein 1 (LOC100153931) antibody
  • 8430401L15Rik antibody
  • AI447519 antibody
  • dJ400N23 antibody
  • Mazr antibody
  • Patz antibody
  • RIAZ antibody
  • ZBTB19 antibody
  • Zfp278 antibody
  • Znf278 antibody
  • ZSG antibody

Protein level used designations for ZNF278

zinc finger protein 278 , BTB-POZ domain zinc finger transcription factor , BTB/POZ domain zinc finger transcription factor , MAZ-related factor , POZ-, AT hook-, and zinc finger-containing protein 1 , POZ-AT hook-zinc finger protein , protein kinase A RI subunit alpha-associated protein , zinc finger and BTB domain-containing protein 19 , zinc finger sarcoma gene protein , POZ and AT hook containing zinc finger 1 long C isoform , transcription factor (MAZ-related) MAZR

GENE ID SPECIES
100058375 Equus caballus
733194 Xenopus laevis
416963 Gallus gallus
23598 Homo sapiens
486365 Canis lupus familiaris
100328729 Oryctolagus cuniculus
56218 Mus musculus
305471 Rattus norvegicus
532416 Bos taurus
100153931 Sus scrofa
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