Zinc Finger Protein 278 Proteins
The protein encoded by ZNF278 contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation.
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Zinc Finger Protein 278 (ZNF278) (AA 1-687) protein (His tag) Protein
Zinc Finger Protein 278 (ZNF278) protein (His tag) Protein
Zinc Finger Protein 278 (ZNF278) protein (His tag) Protein
Zinc Finger Protein 278 (ZNF278) (AA 1-537) protein (GST tag) Protein
Zinc Finger Protein 278 (ZNF278) (AA 260-358) protein (GST tag) Protein
Zinc Finger Protein 278 (ZNF278) Protein Profile
Protein Summary
The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated t1\;22p36.1\;q12. The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.
Gene names and symbols associated with ZNF278
- POZ/BTB and AT hook containing zinc finger 1 (PATZ1) antibody
- POZ/BTB and AT hook containing zinc finger 1 S homeolog (patz1.S) antibody
- POZ (BTB) and AT hook containing zinc finger 1 (Patz1) antibody
- POZ-, AT hook-, and zinc finger-containing protein 1 (LOC100153931) antibody
- 8430401L15Rik antibody
- AI447519 antibody
- dJ400N23 antibody
- Mazr antibody
- Patz antibody
- RIAZ antibody
- ZBTB19 antibody
- Zfp278 antibody
- Znf278 antibody
- ZSG antibody
Protein level used designations for ZNF278
zinc finger protein 278 , BTB-POZ domain zinc finger transcription factor , BTB/POZ domain zinc finger transcription factor , MAZ-related factor , POZ-, AT hook-, and zinc finger-containing protein 1 , POZ-AT hook-zinc finger protein , protein kinase A RI subunit alpha-associated protein , zinc finger and BTB domain-containing protein 19 , zinc finger sarcoma gene protein , POZ and AT hook containing zinc finger 1 long C isoform , transcription factor (MAZ-related) MAZR
GENE ID | SPECIES |
---|---|
100058375 | Equus caballus |
733194 | Xenopus laevis |
416963 | Gallus gallus |
23598 | Homo sapiens |
486365 | Canis lupus familiaris |
100328729 | Oryctolagus cuniculus |
56218 | Mus musculus |
305471 | Rattus norvegicus |
532416 | Bos taurus |
100153931 | Sus scrofa |
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