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ZNF334 encodes a member of the C2H2 zinc finger family.
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results obtained in vitro for helper lymphocytes of healthy individuals seem to mimic the regulatory effect of TNFalpha (show TNF Proteins) on the expression of ZNF334 in the cells of RA patients
This gene encodes a member of the C2H2 zinc finger family. The encoded protein contains a Krueppel-associated box, fourteen C2H2 zinc finger domains, and four C2H2-type\\/integrase DNA-binding domains. Decreased expression of this gene may be a marker for rheumatoid arthritis. Alternative splicing results in multiple transcript variants that encode different protein isoforms.