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The protein encoded by ZNF335 enhances transcriptional activation by ligand-bound nuclear hormone receptors. Additionally we are shipping ZNF335 Kits (10) and and many more products for this protein.
Showing 10 out of 25 products:
Human Polyclonal ZNF335 Primary Antibody for IHC, IP - ABIN251019
Garapaty, Mahajan, Samuels: Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1. in The Journal of biological chemistry 2008
ZNF335 gene mutation is associated with extreme microcephaly with a severely simplified gyral pattern, decreased brain size, increased extra-axial space, enlarged ventricles, absence of the corpus callosum and delayed myelination
In this article, we describe another family harboring ZNF335 mutations. The mutations were individually transmitted by her parents, indicating that the proband was compound heterozygous for the mutations. We speculate that invisible basal ganglia may be the key feature of ZNF335 mutations.
we performed a meta-analysis of our data with the previous reports, identifying two further loci harbouring the ZNF335 and NIFA (show INA Antibodies) genes which now exceed genome-wide significance, taking the total number of CD susceptibility loci to 42.
NIF-1 expression is associated with tumor grade in bladder cancer.
Study identifies and characterizes a nuclear zinc finger protein, ZNF335/NIF-1, as a causative gene for severe microcephaly, small somatic size, and neonatal death.
CCR4 (show CCR4 Antibodies) plays a role in the regulation of certain endogenous RARalpha (show RARA Antibodies) target genes and RCD1 (show RQCD1 Antibodies) and CCR4 (show CCR4 Antibodies) might mediate their function through their interaction with NIF-1
NRC-interacting factor 1 is a novel cotransducer that interacts with and regulates the activity of the nuclear hormone receptor (show NR0B1 Antibodies) coactivator NRC (show NCOA6 Antibodies)
p35 (show CDK5R1 Antibodies) interacts with NIF-1 and regulates the subcellular localization of the protein independent of Cdk5 (show CDK5 Antibodies)-dependent phosphorylation. ...reveal a new mechanism of p35 (show CDK5R1 Antibodies) in transcriptional regulation that does not require the kinase activity of Cdk5 (show CDK5 Antibodies)
Results suggest that NIF-1 directs neuronal morphogenesis during early developmental stages through modulating activity-dependent gene transcription
Zinc finger protein Zfp335 is required for the formation of the naive T cell compartment.
Znf335 null mice are embryonically lethal, and conditional knockout leads to severely reduced cortical size.
The protein encoded by this gene enhances transcriptional activation by ligand-bound nuclear hormone receptors. However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear hormone receptor transcriptional coactivator NRC. The encoded protein may function by altering local chromatin structure.
NRC-interacting factor 1
, zinc-finger/leucine-zipper co-transducer NIF1
, zinc-finger/leucine-zipper co-transducer NIF-1