Zinc Finger Protein 36, C3H Type, Homolog (Mouse) Proteins (ZFP36)

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Additionally we are shipping ZFP36 Antibodies (82) and ZFP36 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZFP36 7538 P26651
Mouse ZFP36 ZFP36 22695 P22893
Rat ZFP36 ZFP36 79426 P47973
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Top ZFP36 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,871.00
Details

ZFP36 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

Top referenced ZFP36 Proteins

  1. Human ZFP36 Protein expressed in Wheat germ - ABIN1325745 : McDermott, Ellis, Bou-Gharios, Clegg, Tew: RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes. in Osteoarthritis and cartilage 2016 (PubMed)

More Proteins for Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) Interaction Partners

Human Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) interaction partners

  1. The role of TTP (show ADAMTS13 Proteins) in human cancers and immunity.[review]

  2. Findings reveal tristetraprolin, which is known to bind COX-2 mRNA and promote its rapid degradation, as regulator of COX-2 expression in influenza A viruses (IAV) infection. During IAV replication and viral RNA accumulation TTP (show ADAMTS13 Proteins) mRNA synthesis was induced, resulting in reduced COX-2 levels.

  3. our data demonstrate that TTP (show ADAMTS13 Proteins) acts as a regulator of mitochondrial dynamics through enhancing degradation of alpha-Syn mRNA in cancer cells. This finding will increase understanding of the molecular basis of mitochondrial dynamics.

  4. Suggest that TTP (show ADAMTS13 Proteins) is an important prognostic indicator for prostate cancer, and augmenting TTP (show ADAMTS13 Proteins) function would effectively disable the metabolism and proliferation of aggressive prostate tumors.

  5. RAS signaling can upregulate tumor cell PD-L1 (show CD274 Proteins) expression through a mechanism involving increases in PD-L1 (show CD274 Proteins) mRNA stability via modulation of the AU-rich element-binding protein tristetraprolin.

  6. Because TTP (show ADAMTS13 Proteins) also represses IL-1beta (show IL1B Proteins) expression, it is a dual inhibitor of the IL-1beta (show IL1B Proteins) system, regulating expression of the cytokine and the upstream controller NLRP3 (show NLRP3 Proteins)

  7. Data show that the synthetic liver X receptors (LXRs) agonist T0901317 promoted cytokines IL-1beta (show IL1B Proteins), IL-6 (show IL6 Proteins) and TNFalpha (show TNF Proteins) mRNA degradation, destabilized TNFalpha (show TNF Proteins) mRNA through its 3'-untranslated region, and increased the expression of tristetraprolin (TTP).

  8. TTP (show ADAMTS13 Proteins) was demonstrated to destabilize the VEGF (show VEGFA Proteins) mRNA in ARPE-19 cells under hypoxic conditions. Furthermore, CM from TTP (show ADAMTS13 Proteins)-overexpressing ARPE-19 cells suppressed tube formation in HUVECs.

  9. this study shows that TTP (show ADAMTS13 Proteins) is down-regulated in glioma tissue samples and cell lines, and is associated with diminished survival in glioma patients

  10. TTP (show ADAMTS13 Proteins) inhibited the proliferation, migration, and invasion of gastric cancer cell lines through regulation of IL-33 (show IL33 Proteins).

Pig (Porcine) Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) interaction partners

  1. direct interaction between TTP protein and porcine TNF-alpha (show TNF Proteins) mRNA ARE probe

Mouse (Murine) Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) interaction partners

  1. mRNA-binding protein tristetraprolin (TTP) is induced by iron deficiency and degrades mRNAs of mitochondrial Fe/S-cluster-containing proteins, specifically Ndufs1 (show NDUFS1 Proteins) in complex I and Uqcrfs1 (show UQCRFS1 Proteins) in complex III, to match the decrease in Fe/S-cluster availability.

  2. Expression of the RNA-binding protein, tristetraprolin (TTP) was down-regulated in response to calcineurin inhibition.

  3. by utilizing Ttp-/- mice we demonstrated the in vivo anti-inflammatory role of Ttp in radiation pneumonitis.

  4. Results suggest that RNA-binding proteins such as TTP are expressed and perhaps involved in the modulation of inflammation-induced pregnancy pathologies.

  5. The authors found that the endogenous Zfp36 directly interacts with the cytoplasmic poly(A)-binding protein. Importantly, this interaction is required for the translational repression of Zfp36's target mRNAs in resolving inflammation.

  6. degrades p28 (show GSTO1 Proteins) to inhibit IL-27 (show IL27 Proteins) production by macrophages and is thereby a negative regulator of the antitumour response

  7. Results suggest that tristetraprolin (TTP) as a cytoskeletal regulator is required for spindle morphology/chromosome alignment and actin polymerization in oocytes.

  8. RAS signaling can upregulate tumor cell PD-L1 (show CD274 Proteins) expression through a mechanism involving increases in PD-L1 (show CD274 Proteins) mRNA stability via modulation of the AU-rich element-binding protein tristetraprolin.

  9. these data support the hypothesis that TTP plays a role in the post-transcriptional regulation of the ODC (show ODC1 Proteins) mRNA transcript.

  10. Posttranscriptional gene regulation by TTP schedules the termination of the antimicrobial engagement of neutrophils.

ZFP36 Protein Profile

Protein Summary

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).

Gene names and symbols associated with ZFP36

  • ZFP36 ring finger protein (ZFP36)
  • ZFP36 ring finger protein L homeolog (zfp36.L)
  • tristetraproline (EDI_287240)
  • Tristetraproline (Bm1_42085)
  • tristetraproline (LOAG_03119)
  • similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth (ZFP36)
  • ZFP36 ring finger protein (zfp36)
  • zinc finger protein 36 (Zfp36)
  • ZFP36 ring finger protein (Zfp36)
  • C3H-1 protein
  • g0s24 protein
  • Gos24 protein
  • Nup475 protein
  • rnf162a protein
  • Tis11 protein
  • TIS11D protein
  • TISII protein
  • Ttp protein
  • Zfp-36 protein
  • ZFP36 protein

Protein level used designations for ZFP36

G0/G1 switch regulatory protein 24 , growth factor-inducible nuclear protein NUP475 , tristetraprolin , tristetraproline , zinc finger protein 36 homolog , zinc finger protein 36, C3H type, homolog , zinc finger protein, C3H type, 36 homolog , CCCH zinc finger protein C3H-1 , Tristetraproline , TIS11 , TTP , zfp-36 , zinc finger protein homologous to Zfp-36 in mouse , similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth , zinc finger protein 36, C3H type, homolog (mouse) , CCCH (CX8CX5CX3H) zinc finger domain RNA-binding protein , TPA-induced sequence 11 , TNF alpha inhibitor , Tax interacting protein

GENE ID SPECIES
7538 Homo sapiens
398102 Xenopus laevis
5879635 Entamoeba dispar SAW760
6103302 Brugia malayi
9940506 Loa loa
282127 Bos taurus
698280 Macaca mulatta
736203 Pan troglodytes
100127733 Xenopus (Silurana) tropicalis
100316849 Sus scrofa
22695 Mus musculus
79426 Rattus norvegicus
484510 Canis lupus familiaris
443283 Ovis aries
100733110 Cavia porcellus
100340391 Oryctolagus cuniculus
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