Zinc Finger Protein 42 Proteins (ZFP42)

Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Additionally we are shipping ZFP42 Antibodies (102) and ZFP42 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZFP42 132625 Q96MM3
Mouse ZFP42 ZFP42 22702 P22227
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Top ZFP42 Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days

ZFP42 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Zinc Finger Protein 42 (ZFP42) Interaction Partners

Human Zinc Finger Protein 42 (ZFP42) interaction partners

  1. ZFP42 missense mutation was identified in patients with multilocus imprinting disturbances. ZFP42 pathogenic mutation affects protein conformation and activity.

  2. Results provide evidence that bFGF regulates stemness maintenance in stem cells isolated from human exfoliated deciduous teeth (SHEDs) by enhancing REX-1 mRNA expression via the FGFR and Akt signaling pathways. Moreover, IL-6 is also involved in the bFGF-induced REX1 expression.

  3. Results show that a novel pluripotency regulator, REX1, is essential for pluripotency and reprogramming.

  4. reduced expression protein-1 (REX-1) is widely expressed in human skin and may be involved in cutaneous differentiation but not in stem cell fate determination.

  5. hRex1 binds to the hRex1 promoter region at -298 bp and positively regulates hRex1 transcription, but this regulation is lost in PC-3 human prostate cancer cells.

  6. REX1 functions in normal adult epithelial cells and tumorigenic stem cells.

  7. Data show that Oct-4, Rex-1, and Gata-4 expression in human mesenchymal stem cells increases cell differentiation efficiency but not hTERT expression.

  8. expression of REX-1 in meiotic cells from both testes and ovary indicate a role in meiosis.

  9. MAPCs express the OCT4 and REX1 transcription factors, two specific markers of undifferentiated embryonic stem (ES) cells.

Mouse (Murine) Zinc Finger Protein 42 (ZFP42) interaction partners

  1. RNF12 targets pluripotency protein REX1 for degradation to initiate random X chromosome inactivation in embryonic stem cells.

  2. Data show that zinc finger protein 42 (Rex1) and zinc finger and SCAN domain containing 4D/4C (Zscan4D/4C) correlate with the cell-cycle length under different mechanisms.

  3. Results show that a novel pluripotency regulator, REX1, is essential for pluripotency and reprogramming.

  4. Rex1 plays a role during preimplantation development and alters expression levels of Zscan4.

  5. Results show that Rex1 regulates endogenous retroviral element expression in mouse embryonic stem cells and during pre-implantation development and suggest that Rex1 and its relatives have evolved as regulators of endogenous retroviral transcription.

  6. RNF12 causes REX1 breakdown through dose-dependent catalysis, thereby representing an important pathway to initiate X-chromosome inactivation

  7. the involvement of Rex-1 in control of Polycomb target genes during pluripotency or differentiation.

  8. loss of Rex1 leads to impaired testicular function.

  9. the functional connection of Rex1 to genomic imprinting represents another case where newly made genes have co-evolved with lineage-specific phenomena.

  10. Rex-1 transcription factor regulates the differentiation of F9 stem cells along several distinct cell lineages found in the early embryo.

  11. Embryonic stem cell marker Rex-1 and the pluripotent stem cell marker Oct-4 are spontaneously expressed by untreated mesenchymal stem cells.

  12. Rex-1 marker was assessed using flow cytometry and gene expression profiling.

  13. Rex1, which is highly expressed in stem cells, inhibits signaling via the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway, thereby modulating the differentiation of F9 cells.

  14. Rex1 should be regarded just as a marker of pluripotency without functional significance

  15. The disruption of the Rex1 gene enhanced the expression of ectoderm, mesoderm, and endoderm markers as compared to wild-type embryonic stem cells

ZFP42 Protein Profile

Protein Summary

Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal.

Gene names and symbols associated with Zinc Finger Protein 42 Proteins (ZFP42)

  • ZFP42 zinc finger protein (ZFP42)
  • zinc finger protein 42 (Zfp42)
  • zinc finger protein 42 (ZFP42)
  • Rex-1 protein
  • Rex1 protein
  • Zfp-42 protein
  • ZFP42 protein
  • ZNF754 protein

Protein level used designations for Zinc Finger Protein 42 Proteins (ZFP42)

REX-1 , REX1 transcription factor , hREX-1 , reduced expression protein 1 , zfp-42 , zinc finger protein 42 homolog , zinc finger protein 754 , mREX-1 , zinc finger protein 42

132625 Homo sapiens
22702 Mus musculus
100037940 Sus scrofa
100856057 Canis lupus familiaris
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