anti-Zinc Finger Protein 423 (104125) Antibodies

The protein encoded by 104125 is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
104125 94187 Q80TS5
104125 94188 O08961
104125 23090 Q2M1K9
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Top anti-Zinc Finger Protein 423 Antibodies at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ZNF423 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HT1080 cell lysate 100 μL 2 to 3 Days
$319.00
Details
Human Goat Un-conjugated ELISA, WB ABIN308409 Immunofluorescence analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing nuclear staining. Actin filaments were stained wit ABIN308409 Flow cytometric analysis of paraformaldehyde fixed Kelly cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) fo 0.1 mg 6 to 7 Days
$286.39
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-ZNF423/OAZ Polyclonal Antibody, Unconjugated (ABIN1385826) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
$317.90
Details
Human Goat Un-conjugated ELISA   100 μg 11 to 14 Days
$610.50
Details
Cow Rabbit Un-conjugated WB ZNF423 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Details
Human Rabbit Un-conjugated WB   400 μL 11 to 14 Days
$493.17
Details
Human Goat Un-conjugated ELISA   100 μg 11 to 16 Days
$682.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL 3 to 7 Days
$317.90
Details
Human Goat Un-conjugated ELISA   100 μg 11 to 12 Days
$356.00
Details

More Antibodies against Zinc Finger Protein 423 Interaction Partners

Mouse (Murine) Zinc Finger Protein 423 (104125) interaction partners

  1. In vivo, vitamin A supplementation prevents obesity, downregulates Gadd45a expression, and reduces GADD45A binding and DNA demethylation in the Zfp423 promoter.

  2. ZFP423 to be expressed in the developing cortex and promote RA-dependent neuronal differentiation.

  3. Zfp423/ZNF423 has a role in regulating cell cycle progression, the mode of cell division and the DNA-damage response in Purkinje neuron progenitors

  4. These data identify Zfp423 as a molecular brake on adipocyte thermogenesis.

  5. loss of Zfp423 alters expression of several genes encoding key cilium components, including increased expression of Tulp3. Tulp3 is a direct binding target of Zfp423 and reducing the overexpression of Tulp3 in Zfp423-deficient cells suppresses Smoothened translocation defects.

  6. Data show that the expression of miR-195a is regulated during adipocyte differentiation and identified Zfp423 as its novel target.

  7. the antiadipogenic function of Zfp521 is mostly exerted through repression of Zfp423 and the downstream target PPAR-gamma gene.

  8. Zfp423 binds autoregulatory sites in a developmental cell culture model.

  9. Maternal obesity enhanced Zfp423 expression and adipogenic differentiation during fetal development, at least partially through reducing DNA methylation in the Zfp423 promoter.

  10. Constitutive expression of a C-terminal mutant OAZ that selectively disrupts OAZ-O/E interaction while retaining other activities, exhibits apparently normal OSN differentiation.

  11. Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells.

  12. Zfp423(-/-) hemisphere malformations are shaped by both genetic and non-genetic factors to produce distinct phenotypes.

  13. ZFP423 coordinates Notch1 and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expression.

  14. Zfp423 as a transcriptional regulator of preadipocyte determination

  15. Ebfaz can substitute for the upregulated expression of Evi3 in B-cell disease and has a role in hematopoietic cancer

  16. Homozygous Zfp423 null mice are runted and ataxic, the cerebellum is underdeveloped, and the vermis is severely reduced. In the remaining cerebellar structures, the Purkinje cells are poorly developed and mislocalized.

  17. Neural precursor proliferation is reduced in Zfp423 null cerebellum, especially near the midline. Radial glia are morphologically abnormal. Cell layers appear nearly normal to grossly disorganized.

  18. these experiments suggest that OAZ participates in a developmental switch regulating the transition from differentiation to maturation in ORNs.

  19. Enhanced expression of p210BCR/ABL and aberrant expression of Zfp423/ZNF423 induce blast crisis of chronic myelogenous leukemia.

Xenopus laevis Zinc Finger Protein 423 (104125) interaction partners

  1. ZFP423 coordinates Notch1 and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expression.

Human Zinc Finger Protein 423 (104125) interaction partners

  1. We identified calmodulin-like protein 3 (CALML3) as a key sensor of this SNP and a coregulator of ERalpha, which contributes to differential gene transcription regulation in an estrogen and SERM-dependent fashion. Furthermore, using CRISPR/Cas9-engineered ZR75-1 breast cancer cells with different ZNF423 SNP genotypes, striking differences in cellular responses to SERMs and PARP inhibitors, alone or in combination

  2. We report that CTSO reduces the protein levels of BRCA1 and ZNF423 through cysteine proteinase-mediated degradation. We also have identified a series of transcription factors of BRCA1 that are regulated by CTSO at the protein level.

  3. two multi-zinc finger transcription cofactors named ZNF423 and ZNF521 have been characterised as potent inhibitors of EBF1 and are emerging as potentially relevant contributors to the development of B-cell leukaemias

  4. ZNF423 expression is associated with poor outcome of ETV6-RUNX1-negative B precursor acute lymphoblastic leukemia patients.

  5. OAZ gene expression was highly enriched in mesenchymal stem cells (MSCs) compared with peripheral blood leukocytes and was increased in patients with systemic lupus erythematosus (SLE) compared with control subjects.

  6. These findings suggest that expression of UBR5-ZNF423 protein might contribute to the transformation of a subset of Nasopharyngeal carcinoma

  7. Study identifies by whole-exome resequencing, mutations of MRE11, ZNF423, and CEP164 as causing Nephronophthisis-related ciliopathies.

  8. Elevated expression of OAZ transcripts in systemic lupus erythematosus PBLs were strongly correlated with disease activity.

  9. The expression level of OAZ mRNA in the bone marrow and peripheral blood of SLE patients was significantly increased than those observed in normal controls.

  10. Low ZNF423 expression is associated with neuroblastoma.

Cow (Bovine) Zinc Finger Protein 423 (104125) interaction partners

  1. Zfp423 is a critical regulator of adipogenesis in stromal vascular cells of bovine muscle.

Zinc Finger Protein 423 (104125) Antigen Profile

Protein Summary

The protein encoded by this gene is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. It functions as a DNA-binding transcription factor by using distinct zinc fingers in different signaling pathways. Thus, it is thought that this gene may have multiple roles in signal transduction during development. Mutations in this gene are associated with nephronophthisis-14 and Joubert syndrome-19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with 104125

  • zinc finger protein 423 (Zfp423) antibody
  • zinc finger protein 423 (znf423) antibody
  • zinc finger protein 423 L homeolog (znf423.L) antibody
  • zinc finger protein 423 (ZNF423) antibody
  • zinc finger protein 423 (Znf423) antibody
  • ataxia1 antibody
  • ebfaz antibody
  • JBTS19 antibody
  • mKIAA0760 antibody
  • NPHP14 antibody
  • nur12 antibody
  • OAZ antibody
  • roaz antibody
  • si:ch211-212o1.3 antibody
  • wu:fc95d03 antibody
  • zfp104 antibody
  • ZFP423 antibody
  • Znf423 antibody

Protein level used designations for 104125

early B-cell factor associated zinc finger protein , early B-cell factor associated zinc finger transcription factor , early B-cell factor-associated zinc finger protein , olf1/EBF-associated zinc finger protein , smad- and Olf-interacting zinc finger protein , zinc finger protein 104 , Olf-1/EBF associated Zn finger protein Roaz , OLF-1/EBF associated zinc finger , Smad- and Olf-interacting zinc finger protein , hOAZ , zinc finger protein 423

GENE ID SPECIES
94187 Mus musculus
94188 Rattus norvegicus
325643 Danio rerio
100310816 Xenopus laevis
23090 Homo sapiens
487291 Canis lupus familiaris
508025 Bos taurus
100726152 Cavia porcellus
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