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ZNF750 encodes a protein with a nuclear localization site and a C2H2 zinc finger domain. Additionally we are shipping Zinc Finger Protein 750 Antibodies (30) and and many more products for this protein.
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Human ZNF750 Protein expressed in Escherichia coli (E. coli) - ABIN2736118
Boxer, Barajas, Tao, Zhang, Khavari: ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes. in Genes & development 2014
BENI expression is regulated by activin-like signaling, and that this regulation is crucial for Xbra expression and convergent extension during gastrulation.
ZNF750 acts as a potential tumor suppressor gene, and regulates tumor microenvironment.
The low expression of ZNF750 was significantly associated with a poor prognosis.
ZNF750 expression predicts sensitivity to CRT and can be a biomarker that reliably predicts the response of ESCC to CRT.
ZNF750 Mutation is associated with esophageal squamous cell carcinoma.
Suggest no connection of ZNF750 variants with psoriasis or its subphenotypes.
ZNF750 thus controls differentiation in concert with RCOR1 and CTBP1/2 by acting with either KDM1A to repress progenitor genes or KLF4 to induce differentiation genes.
ZNF750 was specifically expressed in the epidermal suprabasal layers and its expression was augmented during differentiation, both in human skin and in-vitro, peaking in the granular layer.
ZNF750 directly links a tissue-specifying factor, p63, to an effector of terminal differentiation, KLF4.
Two haplotypes of ZNF750 and rare 5' regulatory variants of ZNF750 were found to be associated with psoriasis.
ZNF750 mutations could contribute to psoriasis susceptibility.
ZNF750/MPZL3 pathway plays a critical role in the pathogenesis of seborrheic dermatitis
This gene encodes a protein with a nuclear localization site and a C2H2 zinc finger domain. Mutations in this gene have been associated with seborrhea-like dermatitis with psoriasiform elements.
, zinc finger protein 750
, superficial protein 1
, Protein ZNF750
, brachyury expression nuclear inhibitor