Zinc Finger and BTB Domain Containing 24 Proteins (ZBTB24)

ZBTB24 encodes a protein similar to a protein in rodents which is induced by bone morphogenic protein 2 in vitro. Additionally we are shipping ZBTB24 Antibodies (44) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZBTB24 9841 O43167
Mouse ZBTB24 ZBTB24 268294 Q80X44
ZBTB24 365590 Q3B725
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Top ZBTB24 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 11 Days
$291.50
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$4,055.33
Details

ZBTB24 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Rat (Rattus)

More Proteins for Zinc Finger and BTB Domain Containing 24 (ZBTB24) Interaction Partners

Human Zinc Finger and BTB Domain Containing 24 (ZBTB24) interaction partners

  1. Here, we performed a comparative analysis of perturbed DNA methylation landscapes in a cohort of ICF patients using an array-based assay to (i) evaluate the similarities and differences in methylation landscapes depending on patient genotypes as an index of a functional link between the four ICF factors, (ii) identify genomic regions that rely on DNMT3B, ZBTB24, CDCA7 or HELLS for their methylation status

  2. data indicate that SRRM4 regulates alternative RNA splicing of the Bif-1 gene that enables PCa cells resistant to apoptotic stimuli under anti-cancer therapies, and may contribute to AdPC progression into t-NEPC.

  3. The biallelic deletion of ZBTB24 provides strong support for the hypothesis that most ICF2 patients suffer from a ZBTB24 loss of function mechanism and confirms that complete absence of ZBTB24 is compatible with human life. This is in contrast to the observed early embryonic lethality in mice lacking functional Zbtb24

  4. Transcriptome analysis identified Cdca7 as the top down-regulated gene in Zbtb24 homozygous mutant mESCs, which can be restored by ectopic ZBTB24 expression. Finally, we show that this regulation is conserved between species and that CDCA7 levels are reduced in patients carrying ZBTB24 nonsense mutations

  5. Downregulation of ZBTB24 increases the expression of IRF-4 and reduces b-cell proliferation.

  6. Our results demonstrate a novel role of Bif-1 in hepatocellular carcinoma (HCC), in which Bif-1 promotes cell metastasis by regulating Cdc42 expression and activity.

  7. ICF2, caused by biallelic ZBTB24 gene mutations, is acknowledged primarily as an isolated B-cell defect.

  8. This suggests that Bif-1 protein expression may be a useful prognostic marker in early-stage CRC

  9. Clinical and genetic data of mutations in DNMT3B and ZBTB24 in patients with ICF syndrome, were compared.

  10. We report three novel ZBTB24 mutations in Japanese and Cape Verdean type 2 ICF syndrome patients.

  11. A novel deletion in the ZBTB24 gene was responsible for causing immunodeficiency, centromeric instability and facial anomalies syndrome type 2 in this family.

  12. These data indicate that ZBTB24 is involved in DNA methylation of juxtacentromeric DNA and in B cell development and/or B and T cell interactions.

Mouse (Murine) Zinc Finger and BTB Domain Containing 24 (ZBTB24) interaction partners

  1. The biallelic deletion of ZBTB24 provides strong support for the hypothesis that most ICF2 patients suffer from a ZBTB24 loss of function mechanism and confirms that complete absence of ZBTB24 is compatible with human life. This is in contrast to the observed early embryonic lethality in mice lacking functional Zbtb24

  2. Transcriptome analysis identified Cdca7 as the top down-regulated gene in Zbtb24 homozygous mutant mESCs, which can be restored by ectopic ZBTB24 expression. Finally, we show that this regulation is conserved between species and that CDCA7 levels are reduced in patients carrying ZBTB24 nonsense mutations

  3. mutation of human Zbtb24 causes ICF syndrome

  4. consistent induction of ZNF450 by BMP-2 after 4 h in three murine pluripotent cell lines suggests that ZNF450 may play a role in the BMP-2 signalling pathway

ZBTB24 Protein Profile

Protein Summary

This gene encodes a protein similar to a protein in rodents which is induced by bone morphogenic protein 2 in vitro.

Gene names and symbols associated with ZBTB24

  • zinc finger and BTB domain containing 24 (ZBTB24)
  • zinc finger and BTB domain containing 24 (Zbtb24)
  • zinc finger and BTB domain containing 24 (zbtb24)
  • BC055367 protein
  • Bif1 protein
  • Bif1a protein
  • Bsg1 protein
  • ICF2 protein
  • PATZ2 protein
  • zfp450 protein
  • zgc:194556 protein
  • ZNF450 protein

Protein level used designations for ZBTB24

POZ (BTB) and AT hook containing zinc finger 2 , zinc finger and BTB domain-containing protein 24 , zinc finger protein 450 , BMP-induced factor 1 , bone morphogenetic protein-induced factor 1 , brain specific protein 1 , bone morphogenic protein-induced factor-1 alpha isoform

GENE ID SPECIES
9841 Homo sapiens
268294 Mus musculus
365590 Rattus norvegicus
553955 Danio rerio
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