anti-alpha 1 Microglobulin/bikunin (AMBP) Antibodies

AMBP encodes a complex glycoprotein secreted in plasma. Additionally we are shipping alpha 1 Microglobulin/bikunin Kits (134) and alpha 1 Microglobulin/bikunin Proteins (51) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AMBP 259 P02760
AMBP 25377 Q64240
AMBP 11699 Q07456
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Top anti-alpha 1 Microglobulin/bikunin Antibodies at

Showing 10 out of 194 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: Ambp Sample Type: Rat Pancreas lysates Antibody Dilution: 0.125ug/ml 100 μL 2 to 3 Days
Cow Rabbit Un-conjugated WB WB Suggested Anti-AMBP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate WB Suggested Anti-AMBP  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Hela cell lysate 100 μL 2 to 3 Days
Cow Rabbit Un-conjugated WB WB Suggested Anti-Ambp Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Rat Lung 100 μL 2 to 3 Days
Human Mouse Un-conjugated IF, ELISA, WB 100 μg 11 to 14 Days
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Human Serum; ;Primary Ab: 2µg/ml Rabbit Anti-Human a1M Antibody;Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;(Catalog: SAA544Rb19) 100 μg 15 to 18 Days
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Mouse Serum. 100 μg 15 to 18 Days
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: 293T B: A431 10% SDS PAGE antibody diluted at 1:5000 ICC/IF Image alpha-1-Microglobulin antibody detects alpha-1-Microglobulin protein at cytoplasm by immunofluorescent analysis. Sample: A431 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: alpha-1-Microglobulin protein stained by alpha-1-Microglobulin antibody , diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 μm. 100 μL 3 to 4 Days
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of HepG2 cell lysate, using AMBP Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276919 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days

Top referenced anti-alpha 1 Microglobulin/bikunin Antibodies

  1. Human Monoclonal AMBP Primary Antibody for ELISA, WB - ABIN532700 : Akerström, Lögdberg, Berggård, Osmark, Lindqvist: alpha(1)-Microglobulin: a yellow-brown lipocalin. in Biochimica et biophysica acta 2000 (PubMed)
    Show all 3 Pubmed References

  2. Guinea Pig Monoclonal AMBP Primary Antibody for AC, IF - ABIN5505816 : Babiker-Mohamed, Forsberg, Olsson, Winquist, Nilson, Loegdberg, Akerstroem: Characterization of monoclonal anti-alpha 1-microglobulin antibodies: binding strength, binding sites, and inhibition of lymphocyte stimulation. in Scandinavian journal of immunology 1991 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal AMBP Primary Antibody for IF, IHC (p) - ABIN559860 : Cheng, Wang, Huang, Kao, Lu, Hsiao, Shaw: Differential proteomics analysis of amniotic fluid in pregnancies of increased nuchal translucency with normal karyotype. in Prenatal diagnosis 2011 (PubMed)

More Antibodies against alpha 1 Microglobulin/bikunin Interaction Partners

Human alpha 1 Microglobulin/bikunin (AMBP) interaction partners

  1. AMBP mRNA and protein levels were found to be significantly lower in the oral squamous cell carcinoma (OSCC) tumors and cell lines. The underexpression of AMBP was significantly associated with a high metastatic potential to cervical lymph nodes and a poor overall survival. AMBP was suggested to play an important role in the invasive and migratory ability of OSCC cells.

  2. There were significantly higher serum concentrations of fetal hemoglobin and alpha1-microglobulin and significantly lower first trimester serum concentrations of hemopexin in patients who later developed preeclampsia.

  3. Prophylactic UTI maintains the endothelial barrier function, increases VE-cadherin expression, and inhibits the phosphorylation of VE-cadherin at Tyr658 under inflammatory conditions

  4. Data suggest that Mg2+ or Mn2+ (but not Ca2+) induce a conformational change in inter-alpha-inhibitor (ITIH1 and ITIH2) and a bikunin/chondroitin sulfate-dependent increase in thermodynamic stability; bikunin binds adjacent to the two heavy chains.

  5. Data indicate that two heme groups can be bound simultaneously at separate sites in the antioxidant alpha1-microglobulin.

  6. results indicate a reduced UTI level in CSF of MS and NMO patients. The levels were associated with the severity of the two demyelinating diseases during relapse

  7. Proximal tubular dysfunction, indicated by urine alpha1-microglobulin, was independently associated with kidney function decline in HIV-infected and uninfected women and mortality risk among HIV-infected women.

  8. placental alpha microglobulin-1 is a sensitive and specific test to assess rupture of membranes in patients with an equivocal diagnosis based on simple tests

  9. Heavy chain transfer by tumor necrosis factor-stimulated gene 6 to the bikunin proteoglycan.

  10. Decreased bikunin mRNA level in renal cells might be associated with poor prognosis of renal carcinoma.

  11. The antioxidative protection of cells and collagen by A1M is totally dependent on its C34 amino acid residue.

  12. Label-free quantitative comparison of DN urinary exosomes vs control group and SRM further validation, resulted in the discovery of a panel of three proteins (AMBP, MLL3 and VDAC1) which changes in DN.

  13. The high level of serum AMBP could predict the poor response of the AGC patients.

  14. In pre-term pregnant women with intact membranes, placental alpha-microglobulin-1 in cervicovaginal fluid test rates are more positive in cases of uterine contraction.

  15. our findings suggest that urine bikunin level, as well as proteinuria, could represent a useful parameter for monitoring renal function in those patients that do not present any symptoms of renal insufficiency.

  16. Determined is the first structure of human alpha-1-microglobulin with heavy electron density of the chromophore.

  17. Sulfation of the bikunin chondroitin sulfate chain determines heavy chain.hyaluronan complex formation

  18. High urine alpha-1-microglobulin is associated with interstitial fibrosis and tubular atrophy plus inflammation.

  19. High urine alpha-1-microglobulin is associated with ischemic acute tubular necrosis than other causes of acute kidney injury.

  20. Report prognostic value of urinary alpha 1-macroglobulin in idiopathic membranous nephropathy.

Xenopus laevis alpha 1 Microglobulin/bikunin (AMBP) interaction partners

  1. Study isolated the Xenopus AMBP cDNA and characterized the peptide structure and developmental regulation of the gene expression. The results showed that Xenopus AMBP gene is repressed through the direct action of thyroid hormone upon liver parenchymal cells at the metamorphic climax stage.

Pig (Porcine) alpha 1 Microglobulin/bikunin (AMBP) interaction partners

  1. The aim of this research was to screen polymorphism and to perform association study of porcine AMBP, GC and PPP1R3B genes with meat quality traits.

Mouse (Murine) alpha 1 Microglobulin/bikunin (AMBP) interaction partners

  1. Loss of Ambp led to increased anxiety-like behavior, reduced social and exploratory activity.

  2. Loss of bikunin expression is associated with Embryos failing to Initiate Midgut Rotation.

  3. In this review, the use of genetically targeted mice selectively lacking UTI provides evidence of a therapeutic option for experimental endotoxin-related inflammatory disorders such as acute lung injury and acute liver injury.

  4. expression of the AMBP gene transcript and its two protein products, alpha(1)-microglobulin and bikunin, in embryogenesis

  5. UTI inhibited LPS-induced production of TNF-alpha by inhibiting activation of the extracellular signal-regulated protein kinases 1/2-Egr-1 pathway in monocytes, which might at least partly contribute to reduction of hypotension

  6. UTI protects against systemic inflammatory response and subsequent organ injury induced by bacterial endotoxin.

  7. results indicate that endogenous UTI is protective against acute lung injury induced by bacterial endotoxin, at least partly, via the antioxidative properties

  8. increased sensitivity of Bik-/- mice to lung metastasis in vivo is due to a lack of circulating proteins of the inter-alpha inhibitor family, especially bikunin

  9. UTI reduces NF-kappaB activation and downregulates the expression of its related mediators, followed by the inhibition of neutrophil aggregation and infiltration in hepatic ischemia reperfusion injury

  10. Report impaired liver regeneration with humoral and genetic disturbances in urinary trypsin inhibitor-deficient mice.

  11. UTI protects against severe liver injury and subsequent coagulatory disturbance which was mediated, at least partly, through the suppression of TNF-alpha production along with its antiprotease activity.

alpha 1 Microglobulin/bikunin (AMBP) Antigen Profile

Protein Summary

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.

Gene names and symbols associated with AMBP

  • alpha-1-microglobulin/bikunin precursor (AMBP) antibody
  • alpha-1-microglobulin/bikunin precursor (Ambp) antibody
  • alpha-1-microglobulin/bikunin precursor L homeolog (ambp.L) antibody
  • alpha-1-microglobulin/bikunin precursor (ambp) antibody
  • alpha 1 microglobulin/bikunin (Ambp) antibody
  • A1M antibody
  • AI194774 antibody
  • AMBP antibody
  • ambpl antibody
  • ASPI antibody
  • DKFZp470D2211 antibody
  • EDC1 antibody
  • HI-30 antibody
  • HI30 antibody
  • IATIL antibody
  • Intin4 antibody
  • ITI antibody
  • Itil antibody
  • ITILC antibody
  • MGC64242 antibody
  • UTI antibody
  • zgc:66321 antibody

Protein level used designations for AMBP

bikunin , complex-forming glycoprotein heterogeneous in charge , growth-inhibiting protein 19 , inter-alpha-trypsin inhibitor light chain , protein AMBP , protein HC , trypstatin , uristatin , uronic-acid-rich protein , Alpha-1 microglobulin/bikunin , alpha 1 microglobulin/bikunin , inter-alpha-trypsin inhibitor (protein HC), light , alpha-1-microglobulin/bikunin precursor , alpha-1 microglobulin , Urinary Trypsin Inhibitor , polyprotein , ulinastatin , alpha-1-microglobulin/bikunin , Protein AMBP , alpha-1-microglobulin/bikunin precursor, like

259 Homo sapiens
25377 Rattus norvegicus
280996 Bos taurus
380514 Xenopus laevis
481685 Canis lupus familiaris
742026 Pan troglodytes
770795 Gallus gallus
100136079 Oncorhynchus mykiss
100174099 Pongo abelii
397593 Sus scrofa
100510797 Felis catus
11699 Mus musculus
100379539 Cavia porcellus
101104205 Ovis aries
101840661 Mesocricetus auratus
394093 Danio rerio
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