gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) ELISA Kits

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Additionally we are shipping GABRA3 Antibodies (77) and GABRA3 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GABRA3 2556 P34903
GABRA3 14396 P26049
GABRA3 24947  
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Top GABRA3 ELISA Kits at antibodies-online.com

Showing 4 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human
  96 Tests 15 to 18 Days
$875.60
Details
Rat
  96 Tests 15 to 18 Days
$875.60
Details
Mouse < 0.78 pg/mL n/a   96 Tests 15 to 18 Days
$875.60
Details
Cow
  96 Tests 15 to 18 Days
$1,029.60
Details

More ELISA Kits for GABRA3 Interaction Partners

Human gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) interaction partners

  1. The GABRA3 found distribute in intercalated nucleui of amygdala and dentate gyrus.

  2. These small-molecule GlyR PAMs have high potential both as early tool compounds to enable pharmacological studies of GlyR inhibitory neurotransmission and as a starting point for the development of potent, selective GlyRalpha3 PAMs as novel analgesics.

  3. GABA alpha2 and/or alpha3 receptor subtypes are involved in GABAergic modulation of prolactin secretion.

  4. GABRA3 induced MMP-2 and MMP-9 expression through activation of the JNK/AP-1 signaling pathway, promoting lymphatic metastasis in lung adenocarcinoma.

  5. Five missense variants and one microduplication were detected in four families and two sporadic cases presenting with a range of epileptic seizure types, a varying degree of intellectual disability and developmental delay, sometimes with dysmorphic features or nystagmus.

  6. The alpha3-immunoreactivity in the cerebellar cortex was relatively weak, but it was abundantly observed in different cell populations in the subcortical cerebellar structures

  7. Gabra3 activates the AKT pathway to promote breast cancer cell migration, invasion and metastasis. The A-to-I RNA-edited form of Gabra3 is found only in non-invasive breast cancers. Edited Gabra3 suppresses breast cancer cell invasion and metastasis.

  8. The N-terminal region of GABRA3 and the GlyR beta subunit occupies the same binding site of gephyrin.

  9. high expression of GABBR2 with a low expression of GABR(A3) may predict a better outcome in non-small cell lung cancer

  10. A novel role for GA-repeat core promoter to regulate gene expression in the genes such as GABRA3 involved in development and evolution.

  11. We identified truncating mutations in distinct X-linked gamma-aminobutyric acid A (GABAA) receptor subunit-encoding genes, GABRQ and GABRA3.this is the first report of ASD patients with truncating mutations in GABA receptors genes.

  12. Endogenous potentiation of GABAergic synaptic transmission and responses to GABA uncaging in the thalamic reticular nucleus is absent in mice in which benzodiazepine binding to alpha3 subunit-containing GABAARs is disrupted.

  13. In subjects with schizophrenia, GABA A alpha3 receptor expression is 14% higher in layer 2 of the dorsolateral prefrontal cortex.

  14. The results indicate that there may be specific GABA receptor gene expression variation in migraine, particularly involving the GABRA3 and GABBR2 genes.

  15. The ratios of beta(3)/beta(2) and alpha(5)/alpha(1) subunit protein expression in Angelman syndrome cortex were significantly decreased when compared with controls.

  16. GABRA3 gene was overexpressed in lung cancer and rarely expressed in other cancers

  17. These findings suggest that common variation in the GABRA2, GABRA3, GABRA6, and GABRG2 genes does not play a major role in liability to anxiety spectrum disorders.

  18. extracellular domain models show subunit arrangement of GABA-A receptors

  19. The results of our study indicate that GABRA 3 gene might also be involved in the genetic pathophysiology of unipolar major depressive disorder

  20. 3 of GABRA3 are found to be associated with THPP

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) interaction partners

  1. Absence of the Gabra3 receptor subunit slows recovery from ethanol-induced incoordination.

  2. alpha3 subunit containing GABA(A) receptors as key mediators of the reward-related effects of benzodiazepines

  3. Quantitative trait locus analysis identifies Gabra3 as a regulator of behavioral despair in mice

  4. Despite the exclusive expression of alpha3-containing GABAA receptors in the reticular thalamic nucleus, these receptors do not seem to be critical for the mediation of the effects of diazepam on the sleep EEG

  5. The alpha3 subunit mRNAs first appeared in the differentiating zone at embryonic day 13 (E13). And localized in the developing Purkinje cells and cerebellar nucleus neurons, and disappeared from Purkinje cells by the end of first postnatal week.

  6. GABA-A receptors which contain the alpha3 subunit might be involved in regulation of anxiety.

  7. editing of the Gabra-3 mRNA is important for normal brain development.The extent of editing is low at birth but increases with age, reaching close to 100% in the adult brain.

  8. lack of alpha3-GABA(A) receptors is extensively compensated for to preserve the integrity of thalamo-cortical function in physiological and pathophysiological situations

  9. The phenotypes following global deletion of the GABAA receptor alpha3 subunit provided relevant insights into the potential behavioural relevance of this specific receptor subtypes in the modulation of both affective and cognitive functions.

  10. Deletion of the GABAAR alpha3 subunit reduces evoked thalamic oscillatory activity.

  11. Resutls show that the variation in editing gave receptors like HTR2C and GABA(A) (gamma-aminobutyric acid type A) a different set of protein isoforms during development from those in the adult animal.

Xenopus laevis gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3) interaction partners

  1. Functional studies in Xenopus laevis oocytes revealed a variable but significant reduction of GABA-evoked anion currents for all mutants compared to wild-type receptors. The degree of current reduction correlated partially with the phenotype.

GABRA3 Antigen Profile

Antigen Summary

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

Gene names and symbols associated with GABRA3

  • gamma-aminobutyric acid type A receptor alpha3 subunit (GABRA3) antibody
  • gamma-aminobutyric acid (GABA) A receptor, alpha 3 (gabra3) antibody
  • gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3 (Gabra3) antibody
  • gamma-aminobutyric acid type A receptor alpha3 subunit (Gabra3) antibody
  • gamma-aminobutyric acid receptor subunit alpha-3 (LOC100653496) antibody
  • Gabra-3 antibody
  • GABRA3 antibody
  • si:ch211-113k9.1 antibody

Protein level used designations for GABRA3

GABA(A) receptor subunit alpha-3 , GABA(A) receptor, alpha 3 , gamma-aminobutyric acid receptor subunit alpha-3 , gamma-animobutyric acid (GABA) A receptor, alpha 3 , gamma-aminobutyric acid (GABA) A receptor, alpha 3 , gamma-aminobutyric acid A receptor, alpha 3 , gamma-aminobutyric acid A receptor, alpha 3-like , gamma-aminobutyric acid receptor subunit alpha-3-like , GABA-A receptor alpha-3 subunit , Gamma-animobutyric acid (GABA) A receptor alpha 3 , Gamma-animobutyric acid (GABA) A receptor, alpha 3 , gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 3 , gamma-aminobutyric acid receptor, subunit alpha 3

GENE ID SPECIES
2556 Homo sapiens
282237 Bos taurus
422289 Gallus gallus
465914 Pan troglodytes
492223 Canis lupus familiaris
100063420 Equus caballus
100294524 Felis catus
100349107 Oryctolagus cuniculus
100391222 Callithrix jacchus
100451835 Pongo abelii
100466765 Ailuropoda melanoleuca
100494398 Xenopus (Silurana) tropicalis
100592909 Nomascus leucogenys
14396 Mus musculus
24947 Rattus norvegicus
100653496 Xenopus laevis
100725783 Cavia porcellus
100538116 Danio rerio
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