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The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 188.8.131.52). Additionally we are shipping PFKP Kits (33) and PFKP Proteins (11) and many more products for this protein.
Showing 10 out of 101 products:
Human Polyclonal PFKP Primary Antibody for IHC (p), WB - ABIN392744
Moeller, Dumitrescu, Refetoff: Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes. in Molecular endocrinology (Baltimore, Md.) 2005
Show all 3 Pubmed References
Data indicate that platelet isoform of phosphofructokinase (PFKP) not only is required for metabolic reprogramming and maintaining cell proliferation, but also may be a valid target for anti-renal cancer pharmaceutical agents.
The crystallized PFKP is permanently activated by a deletion of the 22 C-terminal residues.
Anti-human protein S antibody induces tissue factor (show F3 Antibodies) expression through a direct interaction with PFKP and ERK1/2 (show MAPK1/3 Antibodies) activation in coronary artery endothelial cells.
expression of TARDBP (show TARDBP Antibodies) is significantly elevated in HCC (show FAM126A Antibodies) and it regulates the expression of PFKP, the rate-limiting enzyme for glycolysis, through negative regulation of microRNA 520s (miR (show MLXIP Antibodies)-520s).
KLF4 (show KLF4 Antibodies) plays a role in maintenance of high glycolytic metabolism by transcriptional activation of the PFKP gene in breast cancer cells.
PFKP was identified using a trifunctional phenyl sulfonate probe.
Two phosphofructokinase (PFK) chimeras were constructed by exchanging the N- and C-terminal halves of the mammalian M- and C-type isozymes.
PFKP polymorphisms play no apparent role in the development of common forms of obesity in the Danish population.
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 184.108.40.206). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM\; MIM 610681) and liver (PFKL\; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981)
, 6-phosphofructokinase type C
, phosphofructo-1-kinase isozyme C
, phosphofructokinase 1
, 6-phosphofructokinase, platelet type
, Phosphofructokinase, platelet type
, ATP:D-fructose 6-phosphate 1-phosphotransferase
, 6-phosphofructo-1-kinase, C-type
, phosphofructokinase C isozyme
, phosphofructokinase, muscle