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PFKP Products

(phosphofructokinase, Platelet (PFKP))

Categories

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM\; MIM 610681) and liver (PFKL\; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM, Mar 2008].

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Featured PFKP Categories

PFKP Antibodies

High quality antibodies with extensive validation data.

PFKP ELISA Kits

Reliable ELISA kits for a wide range of species.

PFKP Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PFKP Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7434014
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7443050
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7443782
Quantity 100 μL
Datasheet Datasheet

Recommended PFKP ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969277
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969276
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958544
Quantity 96 tests
Datasheet Datasheet

Recommended PFKP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124409
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314755
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314753
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PFKP products

Zhang, Yu, Wang, Yin, Zhao, Li, Li: "Pokeweed antiviral protein attenuates liver fibrosis in mice through regulating Wnt/Jnk mediated glucose metabolism." in: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association, Vol. 24, Issue 3, pp. 157-164, (2018) (PubMed).

Bao, Mukai, Hishiki, Kubo, Ohmura, Sugiura, Matsuura, Nagahata, Hayakawa, Yamamoto, Fukuda, Saya, Suematsu, Minamishima: "Energy management by enhanced glycolysis in G1-phase in human colon cancer cells in vitro and in vivo." in: Molecular cancer research : MCR, Vol. 11, Issue 9, pp. 973-85, (2013) (PubMed).

Yalcin, Clem, Simmons, Lane, Nelson, Clem, Brock, Siow, Wattenberg, Telang, Chesney: "Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases." in: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 24223-32, (2009) (PubMed).

Moeller, Dumitrescu, Refetoff: "Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 12, pp. 2955-63, (2005) (PubMed).

Adam, Sorensen, Cravatt: "Trifunctional chemical probes for the consolidated detection and identification of enzyme activities from complex proteomes." in: Molecular & cellular proteomics : MCP, Vol. 1, Issue 10, pp. 828-35, (2002) (PubMed).

Boulton, Nye, Robbins, Ip, Radziejewska, Morgenbesser, DePinho, Panayotatos, Cobb, Yancopoulos: "ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF." in: Cell, Vol. 65, Issue 4, pp. 663-75, (1991) (PubMed).

Synonyms and alternative names related to PFKP

phosphofructokinase, platelet (pfkp), phosphofructokinase, platelet (PFKP), phosphofructokinase, platelet S homeolog (pfkp.S), ATP-dependent 6-phosphofructokinase, platelet type (LOC100549777), phosphofructokinase, platelet (Pfkp), 1200015H23Rik, 9330125N24Rik, pfk, pfk-c, PFK-C, pfkf, PFKF, PFKM, PFKP

Protein level used designations for PFKP

  • phosphofructokinase, platelet
  • 6-phosphofructokinase type C
  • PFK-C
  • phosphofructo-1-kinase isozyme C
  • phosphofructokinase 1
  • phosphohexokinase
  • 6-phosphofructokinase, platelet type
  • Phosphofructokinase, platelet type
  • ATP:D-fructose 6-phosphate 1-phosphotransferase
  • 6-phosphofructo-1-kinase, C-type
  • phosphofructokinase C isozyme
  • phosphofructokinase, muscle
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