phosphofructokinase, Platelet Proteins (PFKP)

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). Additionally we are shipping PFKP Antibodies (128) and PFKP Kits (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PFKP 5214 Q01813
PFKP 56421 Q9WUA3
PFKP 60416 P47860
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Top PFKP Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,984.89
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$13,984.89
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$672.00
Details
Mammalian Cells Human His tag   50 μg Log in to see 4 Days
$385.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
Details
Escherichia coli (E. coli) Human Un-conjugated SDS-PAGE analysis of Human PFKP Protein. 100 μg Log in to see 11 to 18 Days
$625.39
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$4,313.83
Details
Escherichia coli (E. coli) Mouse T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$704.00
Details
Escherichia coli (E. coli) Rat T7 tag,His tag 100 μg Log in to see 15 to 18 Days
$733.00
Details

PFKP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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More Proteins for phosphofructokinase, Platelet (PFKP) Interaction Partners

Human phosphofructokinase, Platelet (PFKP) interaction partners

  1. Here the authors show that PFK1 (show PFKM Proteins) platelet isoform is upregulated in Glioblastoma and is required for tumor growth mechanistically, such upregulation is due to an increased stability induced by AKT (show AKT1 Proteins) activation via phosphorylation on residue S386.

  2. Data indicate that platelet isoform of phosphofructokinase (PFKP) not only is required for metabolic reprogramming and maintaining cell proliferation, but also may be a valid target for anti-renal cancer pharmaceutical agents.

  3. The crystallized PFKP is permanently activated by a deletion of the 22 C-terminal residues.

  4. Anti-human protein S antibody induces tissue factor expression through a direct interaction with PFKP and ERK1/2 activation in coronary artery endothelial cells.

  5. expression of TARDBP (show TARDBP Proteins) is significantly elevated in HCC (show FAM126A Proteins) and it regulates the expression of PFKP, the rate-limiting enzyme for glycolysis, through negative regulation of microRNA 520s (miR (show MLXIP Proteins)-520s).

  6. KLF4 (show KLF4 Proteins) plays a role in maintenance of high glycolytic metabolism by transcriptional activation of the PFKP gene in breast cancer cells.

  7. PFKP was identified using a trifunctional phenyl sulfonate probe.

  8. Two phosphofructokinase (PFK) chimeras were constructed by exchanging the N- and C-terminal halves of the mammalian M- and C-type isozymes.

  9. PFKP polymorphisms play no apparent role in the development of common forms of obesity in the Danish population.

PFKP Protein Profile

Protein Summary

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM\; MIM 610681) and liver (PFKL\; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981)

Gene names and symbols associated with PFKP

  • phosphofructokinase, platelet (pfkp)
  • phosphofructokinase, platelet (PFKP)
  • phosphofructokinase, platelet S homeolog (pfkp.S)
  • ATP-dependent 6-phosphofructokinase, platelet type (LOC100549777)
  • phosphofructokinase, platelet (Pfkp)
  • 1200015H23Rik protein
  • 9330125N24Rik protein
  • pfk protein
  • PFK-C protein
  • PFKF protein
  • PFKM protein
  • PFKP protein

Protein level used designations for PFKP

phosphofructokinase, platelet , 6-phosphofructokinase type C , PFK-C , phosphofructo-1-kinase isozyme C , phosphofructokinase 1 , phosphohexokinase , 6-phosphofructokinase, platelet type , Phosphofructokinase, platelet type , ATP:D-fructose 6-phosphate 1-phosphotransferase , 6-phosphofructo-1-kinase, C-type , phosphofructokinase C isozyme , phosphofructokinase, muscle

GENE ID SPECIES
394825 Xenopus (Silurana) tropicalis
450266 Pan troglodytes
100022041 Monodelphis domestica
100037146 Xenopus laevis
100070818 Equus caballus
100173619 Pongo abelii
100229947 Taeniopygia guttata
100549777 Meleagris gallopavo
100561110 Anolis carolinensis
100601116 Nomascus leucogenys
5214 Homo sapiens
56421 Mus musculus
60416 Rattus norvegicus
100009526 Oryctolagus cuniculus
100722738 Cavia porcellus
100521394 Sus scrofa
478019 Canis lupus familiaris
507119 Bos taurus
428411 Gallus gallus
101108592 Ovis aries
Selected quality suppliers for PFKP Proteins (PFKP)
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