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GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Additionally we are shipping rho GTPase Activating Protein 44 Proteins (3) and many more products for this protein.
Showing 10 out of 31 products:
Human Polyclonal ARHGAP44 Primary Antibody for IHC, IHC (p) - ABIN4281526
Galic, Tsai, Collins, Matis, Bandara, Meyer: Dynamic recruitment of the curvature-sensitive protein ArhGAP44 to nanoscale membrane deformations limits exploratory filopodia initiation in neurons. in eLife 2014
Rho GTPase activating protein 44 (ARHGAP44) expression is lower in lung carcinoma compared with normal tissues. The GTP (show AK3 Antibodies) hydrolysis activity on cell division cycle 42 (Cdc42 (show CDC42 Antibodies)) and the expression level of ARHGAP44 are negatively correlated with cell migration and invasion.
RICH2 is implicated in viremic control of HIV-1 in black South African individuals.
Besides the already known chromosome 6 associations, the analysis of low-frequency single nucleotide polymorphisms brought up a new association in the RICH2 gene for progression to AIDS.
Knocking down expression of RICH 2 causes loss of the apical actin network and apical microvilli, an increase in actin bundles at the basal surface, and a reduction in cell height. (RICH 2 protein)
Demonstrates that the (show ARHGAP1 Antibodies) RhoGAP domains of RICH-1 and RICH-2 can catalyze GT (show AK3 Antibodies)P hydrolysis of both Rac (show RAC1 Antibodies)1 and Cdc4 (show CDC42 Antibodies)2, but not of Rho (show RHOA Antibodies)A.
RICH2 knockout animals display a selective and highly significant fear of novel objects and increased stereotypic behavior as well as impairment of motor learning.
These results suggested that Rich2 controls dendritic spine morphogenesis and function via inhibition of Rac1 (show RAC1 Antibodies).
Knock-down of Rich2 or disruption of Rich2-Shank3 (show SHANK3 Antibodies) complex, inhibits dendritic spine enlargement.
Shows that the RhoGAP (show ARHGAP1 Antibodies) domain of the human RICH2 ortholog can catalyze GTP (show AK3 Antibodies) hydrolysis of both Rac1 (show RAC1 Antibodies) and Cdc42 (show CDC42 Antibodies), but not of RhoA (show RHOA Antibodies).
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1.
Rho-type GTPase-activating protein RICH2
, Rho GTPase activating protein 44
, RhoGAP interacting with CIP4 homologs protein 2
, rho GTPase-activating protein 44
, rho GTPase-activating protein RICH2
, Rho GTPase-activating protein RICH2