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Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors.
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Human Monoclonal ARHGEF5 Primary Antibody for ELISA, WB - ABIN563509
Mendrzyk, Korshunov, Benner, Toedt, Pfister, Radlwimmer, Lichter: Identification of gains on 1q and epidermal growth factor receptor overexpression as independent prognostic markers in intracranial ependymoma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2006
Human Polyclonal ARHGEF5 Primary Antibody for ELISA, WB - ABIN250996
Debily, Camarca, Ciullo, Mayer, El Marhomy, Ba, Jalil, Anzisi, Guardiola, Piatier-Tonneau: Expression and molecular characterization of alternative transcripts of the ARHGEF5/TIM oncogene specific for human breast cancer. in Human molecular genetics 2004
Tim protein and DDX11 (show DDX11 Antibodies) physically and functionally interact and act in concert to preserve replication fork progression in perturbed conditions.
Data indicate that Rho guanine nucleotide exchange factor 5 (ARHGEF5) is expressed in most human lung adenocarcinoma tissues and cell lines.
Targeting rho guanine nucleotide exchange factor (show ARHGEF28 Antibodies) ARHGEF5/TIM with auto-inhibitory peptides in human breast cancer.
The auto-inhibitory state of Rho guanine nucleotide exchange factor (show ARHGEF28 Antibodies) ARHGEF5/TIM can be relieved by targeting its SH3 domain (show ITSN1 Antibodies) with rationally designed peptide aptamers.
In conclusion, ARHGEF5/Src (show SRC Antibodies) can be considered as a prognostic biomarker and a therapeutic target for patients with resected NSCLC.
A receiver operating characteristic curve constructed with HSP105 (show HSPH1 Antibodies) and TIM gave a sensitivity of 54.3% and 95% (38/40) specificity in discriminating esophageal squamous cell carcinoma from matched controls.
This study performed whole exome sequencing demonistrated that the true de novo variants represent mutations in genes (KCNH5 (show KCNH5 Antibodies), CLCN4 (show CLCN4 Antibodies), and ARHGEF15 (show ARHGEF15 Antibodies)) not previously associated with epilepsies in humans.
Tim-Tipin (show TIPIN Antibodies) complex might play a role in coupling DNA unwinding and DNA synthesis by directly affecting the catalytic activities of replication fork proteins.
Overexpression of Arhgef5 promoted actin stress fiber remodeling through activating RhoA (show RHOA Antibodies), and the activation of RhoA (show RHOA Antibodies) or Cdc42 (show CDC42 Antibodies) was required for Src (show SRC Antibodies)-induced podosome formation.
association in humans of TIM-1 and hypersensitivity and the relationship between TIM1, hygiene, and the environment.
RhoA (show RHOA Antibodies) guanine nucleotide exchange factor (show ARHGEF12 Antibodies) Arhgef5 regulates immature dendritic cell migration
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.
Rho guanine nucleotide exchange factor (GEF) 5
, rho guanine nucleotide exchange factor 5
, rho guanine nucleotide exchange factor 5-like
, guanine nucleotide regulatory protein TIM
, oncogene TIM
, p60 TIM
, transforming immortalized mammary oncogene