serine/arginine-Rich Splicing Factor 3 Proteins (SRSF3)

The protein encoded by SRSF3 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Additionally we are shipping SRSF3 Antibodies (70) and SRSF3 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SRSF3 6428 P84103
SRSF3 20383 P84104
Rat SRSF3 SRSF3 361814  
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Top SRSF3 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,374.17
Details

SRSF3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Top referenced SRSF3 Proteins

  1. Human SRSF3 Protein expressed in Wheat germ - ABIN1319754 : Walsh, Suchanek, Cyphert, Kohan, Szeszel-Fedorowicz, Salati: Serine arginine splicing factor 3 is involved in enhanced splicing of glucose-6-phosphate dehydrogenase RNA in response to nutrients and hormones in liver. in The Journal of biological chemistry 2013 (PubMed)
    Show all 2 Pubmed References

More Proteins for serine/arginine-Rich Splicing Factor 3 (SRSF3) Interaction Partners

Human serine/arginine-Rich Splicing Factor 3 (SRSF3) interaction partners

  1. Findings reveal the molecular mechanism of SRSF3 in pri-miRNA processing and support the previously proposed explanation for the highly conserved position of CNNC in SRSF3-enhanced pri-miRNA processing.

  2. High expression of SRSF3 is associated with oral squamous cell carcinoma.

  3. RBM4 (show RBM4 Proteins)-SRSF3-MAP4K4 (show MAP4K4 Proteins) constitutes a novel mechanism for manipulating the metastasis of colorectal cancer cells through the JNK1 (show MAPK8 Proteins) signaling pathway.

  4. MicroRNA-1908-5p contributes to the oncogenic function of the splicing factor (show SLU7 Proteins) SRSF3 via NKIRAS2 (show NKIRAS2 Proteins) axis in osteosarcoma cells.

  5. Dehydroepiandrosterone (DHEA) and cortisol modulate SRSF9 (show SFRS9 Proteins) and SRSF3 in a different way and data suggest that the anti-glucocorticoid effect of DHEA, among other mechanisms, is also exerted by modulating the expression of proteins involved in the splicing of the GR pre-mRNA.

  6. that SRSF3 controls the expression of the miR (show MLXIP Proteins)-132/212 cluster through regulating REST expression

  7. Alternative splicing of U2AF1 (show U2AF1 Proteins) reveals a shared repression mechanism for duplicated exons controlled by SRF3.

  8. Introduction of point mutations in the SRSF3-binding site or knockdown of SRSF3 expression in cells reduces human papillomavirus 18 929;3434 splicing and E1;E4 production but activates other, minor 929;3465 and 929;3506 splicing. Knockdown of SRSF3 expression also enhances the expression of E2 and L1 mRNAs.

  9. data indicate that the Human Papillomavirus E2 protein (show UBE2B Proteins) links (show CCDC40 Proteins) the viral replication cycle to epithelial differentiation via SRSF3, a key cellular regulator of high-risk (HR)-HPV gene expression

  10. Results suggested that SRSF3 is associated with the initiation and development of OSCC and may be a biomarker and therapeutic target of OSCC.

Mouse (Murine) serine/arginine-Rich Splicing Factor 3 (SRSF3) interaction partners

  1. SRSF3 regulates the innate immune response in resident microglia.

  2. Data liver/mammary gland expressing Srsf3 siRNA displayed a suppressed level of Srsf3 protein, but not the mRNA.

  3. This study provides the first evidence for a SRSF3-driven genetic programme required for morphological and functional differentiation of hepatocytes that may have relevance for human liver disease and metabolic dysregulation.

  4. Serine arginine splicing factor (show SLU7 Proteins) 3 is involved in enhanced splicing of glucose-6-phosphate dehydrogenase (show G6PD Proteins) RNA in response to nutrients and hormones in liver

  5. SRSF3 and SRSF4 (show SRSF4 Proteins) proteins bind to the 3' ends of the majority of intronless histone transcripts, implicating SRSF3 and SRSF4 (show SRSF4 Proteins) in histone mRNA metabolism.

  6. Results suggest that increased SRp20 expression in tumor cells is a critical step for tumor initiation, progression, and maintenance.

  7. mRNA targets of SRp20 and SRp75 were identified in cycling and neurally induced P19 cells.

  8. Hippocampal mRNA expression of Srp20 is up-regulated only in males during contextual fear memory formation as a specific result of the context/tone-shock association. Changes in expression during LTM formation regulate alternative splicing.

SRSF3 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene.

Gene names and symbols associated with SRSF3

  • serine and arginine rich splicing factor 3 (SRSF3)
  • serine/arginine-rich splicing factor 3 (Srsf3)
  • serine/arginine-rich splicing factor 3 S homeolog (srsf3.S)
  • serine and arginine rich splicing factor 3 (Srsf3)
  • serine/arginine-rich splicing factor 3a (srsf3a)
  • AL024116 protein
  • sfrs3 protein
  • si:zc263a23.9 protein
  • SRP20 protein
  • X16 protein
  • zgc:86626 protein

Protein level used designations for SRSF3

pre-mRNA-splicing factor SRP20 , splicing factor, arginine/serine-rich 3 , splicing factor, arginine/serine-rich, 20-kD , splicing factor, arginine/serine-rich 3 (SRp20) , splicing factor, arginine serine-rich 3 , splicing factor, arginine/serine-rich 3a

GENE ID SPECIES
6428 Homo sapiens
20383 Mus musculus
380152 Xenopus laevis
419815 Gallus gallus
403687 Canis lupus familiaris
540276 Bos taurus
361814 Rattus norvegicus
368925 Danio rerio
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