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SRSF3 Products

(serine/arginine-Rich Splicing Factor 3 (SRSF3))
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene. [provided by RefSeq, Sep 2010].

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Featured SRSF3 Categories

SRSF3 Antibodies

High quality antibodies with extensive validation data.

SRSF3 ELISA Kits

Reliable ELISA kits for a wide range of species.

SRSF3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SRSF3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
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Cat. No. ABIN562839
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC
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  • (7)
Cat. No. ABIN6148465
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (4)
Cat. No. ABIN7185554
Quantity 100 μg
Datasheet Datasheet

Recommended SRSF3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970116
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1157109
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1157111
Quantity 96 tests
Datasheet Datasheet

Recommended SRSF3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
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Cat. No. ABIN1319756
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1319754
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3077594
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our SRSF3 products

Walsh, Suchanek, Cyphert, Kohan, Szeszel-Fedorowicz, Salati: "Serine arginine splicing factor 3 is involved in enhanced splicing of glucose-6-phosphate dehydrogenase RNA in response to nutrients and hormones in liver." in: The Journal of biological chemistry, Vol. 288, Issue 4, pp. 2816-28, (2013) (PubMed).

Cyphert, Suchanek, Griffith, Salati: "Starvation actively inhibits splicing of glucose-6-phosphate dehydrogenase mRNA via a bifunctional ESE/ESS element bound by hnRNP K." in: Biochimica et biophysica acta, Vol. 1829, Issue 9, pp. 905-15, (2013) (PubMed).

Jain, Wordinger, Yorio, Clark: "Spliceosome protein (SRp) regulation of glucocorticoid receptor isoforms and glucocorticoid response in human trabecular meshwork cells." in: Investigative ophthalmology & visual science, Vol. 53, Issue 2, pp. 857-66, (2012) (PubMed).

Moura-Alves, Neves-Costa, Raquel, Pacheco, DAlmeida, Rodrigues, Cadima-Couto, Chora, Oliveira, Gama-Carvalho, Hacohen, Moita: "An shRNA-based screen of splicing regulators identifies SFRS3 as a negative regulator of IL-1? secretion." in: PLoS ONE, Vol. 6, Issue 5, pp. e19829, (2011) (PubMed).

Garbes, Riessland, Hölker, Heller, Hauke, Tränkle, Coras, Blümcke, Hahnen, Wirth: "LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate." in: Human molecular genetics, Vol. 18, Issue 19, pp. 3645-58, (2009) (PubMed).

Gonçalves, Matos, Jordan: "Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways." in: Human molecular genetics, Vol. 18, Issue 19, pp. 3696-707, (2009) (PubMed).

Synonyms and alternative names related to SRSF3

serine and arginine rich splicing factor 3 (SRSF3), serine/arginine-rich splicing factor 3 (Srsf3), serine/arginine-rich splicing factor 3 S homeolog (srsf3.S), serine and arginine rich splicing factor 3 (Srsf3), serine/arginine-rich splicing factor 3a (srsf3a), AL024116, SFRS3, Sfrs3, sfrs3, si:zc263a23.9, SRp20, srp20, SRP20, X16, zgc:86626

Protein level used designations for SRSF3

  • pre-mRNA-splicing factor SRP20
  • splicing factor, arginine/serine-rich 3
  • splicing factor, arginine/serine-rich, 20-kD
  • splicing factor, arginine/serine-rich 3 (SRp20)
  • splicing factor, arginine serine-rich 3
  • splicing factor, arginine/serine-rich 3a
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