anti-serine/threonine Kinase 38 (STK38) Antibodies

Negative regulator of MAP3K1/2 signaling. Additionally we are shipping STK38 Proteins (11) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
STK38 11329 Q15208
STK38 106504 Q91VJ4
STK38 361813  
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Top anti-STK38 Antibodies at antibodies-online.com

Showing 10 out of 121 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-STK38 Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate There is BioGPS gene expression data showing that STK38 is expressed in HepG2 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated EIA, WB The anti-STK38 Pab is used in Western blot to detect STK38 in SK-Br-3 (left) and Jurkat (right) cell line lysates. 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Mouse Un-conjugated ELISA, IF, IHC, IHC (p), IP, WB 100 μg Log in to see 11 to 14 Days
$537.17
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$537.17
Details
Human Mouse Un-conjugated ELISA, IF, IHC, IHC (p), WB 100 μg Log in to see 11 to 14 Days
$537.17
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to STK38 on HeLa cell (antibody concentration 10 µg/mL).  STK38 monoclonal antibody (M01), clone 2G8-1F3 Western Blot analysis of STK38 expression in Hela NE. 100 μg Log in to see 8 to 11 Days
$527.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$550.00
Details
Chicken Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Bat Goat Un-conjugated ELISA, WB 100 μg Log in to see 11 to 14 Days
$610.50
Details

Top referenced anti-STK38 Antibodies

  1. Human Monoclonal STK38 Primary Antibody for RNAi, ELISA - ABIN564920 : Yan, Chu, Qin, Wang, Liu, Jin, Zhang, Gomez, Hergovich, Chen, He, Gao, Yao: Regulation of NDR1 activity by PLK1 ensures proper spindle orientation in mitosis. in Scientific reports 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal STK38 Primary Antibody for IF, IHC (p) - ABIN564922 : Cook, Hoa, Gomez, Gomez, Hergovich: Constitutively active NDR1-PIF kinase functions independent of MST1 and hMOB1 signalling. in Cellular signalling 2014 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal STK38 Primary Antibody for ELISA, WB - ABIN545544 : Tripodis, Mason, Humphray, Davies, Herberg, Trowsdale, Nizetic, Senger, Ragoussis: Physical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex. in Genome research 1999 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal STK38 Primary Antibody for IF, IHC (p) - ABIN564917 : Zhou, Adolfs, Pijnappel, Fuller, Van der Schors, Li, Sugden, Smit, Hergovich, Pasterkamp: MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis. in Molecular and cellular biology 2011 (PubMed)

  5. Human Polyclonal STK38 Primary Antibody for ELISA, WB - ABIN4356615 : Kohler, Schmitz, Cornils, Hemmings, Hergovich: Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases. in Molecular and cellular biology 2010 (PubMed)

More Antibodies against STK38 Interaction Partners

Human serine/threonine Kinase 38 (STK38) interaction partners

  1. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop.

  2. Study provides evidence for an inhibitory role of SOCS2 in TNFalpha induced NF-kappa B activation, identifies NDR1 as a novel substrate of SOCS2, and demonstrates that SOCS2 and TNFalpha induced NF-kappa B signaling are linked through NDR1.

  3. Data show that STK38 supports Ras-driven transformation through promoting detachment-induced autophagy.

  4. a novel and intimate link between the protein kinase NDR1 and TGFbeta signaling

  5. Data establish STK38 as a conserved regulator of autophagy in human cells and flies.

  6. PLK1-mediated phosphorylation protects the binding of Mob1 to NDR1 and subsequent NDR1 activation

  7. STK38-mediated phosphorylation of CDC25A at Ser-76 and the subsequent degradation of CDC25A are required to promote DNA damage-induced G2/M checkpoint activation.

  8. STK38 regulates MYC protein stability and turnover in a kinase activity-dependent manner. STK38 kinase inactivation abrogates apoptosis following B-cell receptor activation, whereas its silencing significantly decreases MYC levels and increases apoptosis.

  9. cyclin D1 has a role in promoting cell cycle progression by enhancing NDR1/2 kinase activity independent of Cdk4

  10. 17-allylamino-17-demethoxygeldanamycin down-regulates STK38, modulating radiosensitivity.

  11. Findings suggest a function of NDR1, which may regulate NF-kappaB activation by its kinase activity.

  12. GSK-3beta inhibits full activation of STK38, and STK38 activation is required to prevent cell death in response to oxidative stress

  13. Findings show a biological role for MICAL-1 in apoptosis and define a novel negative regulatory mechanism of MST-NDR signaling.

  14. These findings establish a novel MST3-NDR-p21 axis as an important regulator of G(1)/S progression of mammalian cells.

  15. Data indicate that human MOB2 is a negative regulator of human NDR kinases in biochemical and biological settings.

  16. NDR1 and NDR2 serine-threonine kinases are regulated by mob proteins

  17. an insert within the catalytic domain between subdomains VII and VIII is autoinhibitory, and the binding of human MOB1 to the N-terminal domain of NDR induces the release of this autoinhibition.

  18. The NDR1 and NDR2 kinases were incorporated into HIV-1 particles and were cleaved by the HIV-1 protease.

  19. In vivo activation of human NDR by membrane-bound hMOBs is dependent on their interaction and occurs solely at the membrane.

  20. These data indicate that NDR-driven centrosome duplication requires Cdk2 activity and that Cdk2-induced centrosome amplification is affected upon reduction of NDR activity.

Mouse (Murine) serine/threonine Kinase 38 (STK38) interaction partners

  1. These results revealed that Stk38 kinase catalyzes the phosphorylation of Rbm24 during sarcomerogensis and this orchestrates accurate sarcomere alignment.

  2. a novel and intimate link between the protein kinase NDR1 and TGFbeta signaling

  3. Stk38 protein kinase has a role in inhibiting TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages

  4. Findings show a biological role for MICAL-1 in apoptosis and define a novel negative regulatory mechanism of MST-NDR signaling.

  5. reduction in the abundances of the NDR proteins NDR1 and NDR2 results in defective responses to proapoptotic stimuli, thereby facilitating the development of tumors

STK38 Antigen Profile

Protein Summary

Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity).

Gene names and symbols associated with STK38

  • serine/threonine kinase 38 (STK38) antibody
  • serine/threonine kinase 38 (Stk38) antibody
  • serine/threonine kinase 38 S homeolog (stk38.S) antibody
  • serine/threonine kinase 38b (stk38b) antibody
  • serine/threonine kinase 38a (stk38a) antibody
  • 5830476G13Rik antibody
  • 9530097A09Rik antibody
  • AA617404 antibody
  • NDR antibody
  • Ndr1 antibody
  • si:ch1073-272h17.2 antibody
  • trc antibody
  • wu:fj80h03 antibody
  • zgc:55572 antibody

Protein level used designations for STK38

NDR1 protein kinase , Ndr Ser/Thr kinase-like protein , nuclear Dbf2-related 1 , nuclear Dbf2-related kinase 1 , serine threonine protein kinase , serine/threonine-protein kinase 38 , nuclear DBF2-related kinase 1 , tricornered , stk38

GENE ID SPECIES
11329 Homo sapiens
106504 Mus musculus
361813 Rattus norvegicus
380110 Xenopus laevis
533677 Bos taurus
428260 Gallus gallus
481766 Canis lupus familiaris
100063891 Equus caballus
100153410 Sus scrofa
100173048 Pongo abelii
100722460 Cavia porcellus
100332206 Danio rerio
406765 Danio rerio
100346979 Oryctolagus cuniculus
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