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May be involved in modulation of TNF response. Additionally we are shipping SDCCAG3 Kits (7) and SDCCAG3 Proteins (6) and many more products for this protein.
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SDCCAG3 has a role in ciliogenesis and in localization of cargo to primary cilia
The novel endosomal protein SDCCAG3 forms a complex with PTPN13 & interacts with GIT1. Interaction of SDCCAG3 with PTPN13 is mediated by the PTPN13 FERM domain & the SDCCAG3 N-terminus. SDCCAG3 expression levels are elevated in colon cancers.
SDCCAG3 is important for protein trafficking and presentation of TNFR1 on the cell surface.
These findings suggest that SDCCAG3 might function in endosomal trafficking downstream of Arf6.
May be involved in modulation of TNF response. May be involved in presentation of TNFRSF1A on the cell surface.
, serologically defined colon cancer antigen 3 homolog