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May be involved in regulating transcriptional activation of cardiac genes during the aging process. Additionally we are shipping serum Response Factor Binding Protein 1 Antibodies (40) and serum Response Factor Binding Protein 1 Kits (7) and many more products for this protein.
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P49/STRAP expression was increased in the old versus young adult mouse hearts and also increased with advancing population doubling levels in cultured human umbilical vein endothelial cells. The increased expression of p49/STRAP in late life may alter the status of histone acetylation and impact mitochondrial dynamics and thereby reduce mitochondrial function and cardiac performance during mammalian senescence.
SRFBP1 is an HCV-specific, pan-genotypic host entry factor.
p49/STRAP may be an important SRF cofactor in the transcriptional regulation of mammalian cardiac muscle genes throughout the life span
p49/STRAP plays a role in the regulation of intracellular processes such as cardiac cellular metabolism, gene expression, and possibly aging.
p49/STRAP can be considered a bona fide co-chaperone of Hsp70 (show HSP70 Proteins).
Overexpression of p49/STRAP reduced actin content in cultured cells and resulted in smaller cell size versus control cells.
49-kDa protein (p49/STRAP) specifically interacts with an acidic amino acid motif (Q7IGSEDG) in the N-terminus of GLUT4 (show SLC2A4 Proteins).
May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells (By similarity).
, SRF-dependent transcription regulation associated protein
, SRF-dependent transcription regulation-associated protein
, serum response factor-binding protein 1
, serum response factor binding protein 1-like