tRNA-Histidine Guanylyltransferase 1-Like (S. Cerevisiae) Proteins (THG1L)

Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. Additionally we are shipping THG1L Antibodies (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
THG1L 54974 Q9NWX6
THG1L 66628 Q9CY52
THG1L 303067 Q5M965
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Top THG1L Proteins at

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Escherichia coli (E. coli) Human His tag 20 μg Log in to see 15 to 19 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 2 to 3 Days

THG1L Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for tRNA-Histidine Guanylyltransferase 1-Like (S. Cerevisiae) (THG1L) Interaction Partners

Human tRNA-Histidine Guanylyltransferase 1-Like (S. Cerevisiae) (THG1L) interaction partners

  1. Study proposes that homozygosity for the p.Val55Ala mutation in tRNA-histidine guanylyltransferase 1 like (THG1L) is the cause of the abnormal mitochondrial network in the patient fibroblasts, likely by interfering with THG1L activity towards MFN2 (show MFN2 Proteins).

  2. The high-resolution crystal structure of human Thg1 reveals remarkable structural similarity between canonical DNA/RNA polymerases and eukaryotic Thg1.

  3. IHG-1 (show FOXC1 Proteins) is a novel regulator of both mitochondrial dynamics and bioenergetic function and contributes to cell survival following oxidant stress. Increased IHG-1 (show FOXC1 Proteins) expression may contribute to pathogenesis of diabetic kidney disease.

  4. IHG-1 increases mitochondrial biogenesis by promoting PGC-1alpha-dependent processes, potentially contributing to the pathogenesis of renal fibrosis

  5. The catalytic domain of Thg1 shares both a common architecture and a two-metal ion-dependent mechanism with canonical 5'-3' DNA polymerases.

  6. ICF45 is a highly conserved novel protein, which is expressed in a cell cycle-dependent manner and seemed to be involved in cell cycle progression and cell proliferation

  7. induced in high glucose-1 (IHG-1 (show FOXC1 Proteins))which increases in diabetic nephropathy, may enhance the actions of TGF-beta1 (show TGFB1 Proteins) and contribute to the development of tubulointerstitial fibrosis

THG1L Protein Profile

Protein Summary

Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis (By similarity).

Gene names and symbols associated with THG1L

  • tRNA-histidine guanylyltransferase 1 like (THG1L)
  • tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) (Thg1l)
  • tRNA-histidine guanylyltransferase 1-like (Thg1l)
  • 1700121M19Rik protein
  • 5730409G07Rik protein
  • AA387658 protein
  • ICF45 protein
  • IHG-1 protein

Protein level used designations for THG1L

probable tRNA(His) guanylyltransferase , tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) , interphase cytoplasmic foci protein 45 , probable tRNA(His) guanylyltransferase-like , induced by high glucose-1 , nterphase cyctoplasmic foci protein 45

416242 Gallus gallus
462226 Pan troglodytes
479315 Canis lupus familiaris
715853 Macaca mulatta
54974 Homo sapiens
66628 Mus musculus
303067 Rattus norvegicus
507084 Bos taurus
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