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Human Monoclonal NOD2 Primary Antibody for FACS, ICC - ABIN151959
McDonald, Chen, Ollendorff, Ogura, Marchetto, Lécine, Borg, Nuñez: A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling. in The Journal of biological chemistry 2005
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Human Polyclonal NOD2 Primary Antibody for ICC, IF - ABIN153051
Till, Rosenstiel, Bräutigam, Sina, Jacobs, Oberg, Seegert, Chakraborty, Schreiber: A role for membrane-bound CD147 in NOD2-mediated recognition of bacterial cytoinvasion. in Journal of cell science 2008
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Human Polyclonal NOD2 Primary Antibody for ELISA, WB - ABIN251672
Keshav: Paneth cells: leukocyte-like mediators of innate immunity in the intestine. in Journal of leukocyte biology 2006
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Human Polyclonal NOD2 Primary Antibody for IHC (fro), IHC (p) - ABIN4340262
Lin, Song, Qin, Li, Li, Zhu, Zhang: Expression of nucleotide-binding oligomerization domain 2 in normal human dental pulp cells and dental pulp tissues. in Journal of endodontics 2009
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Human Polyclonal NOD2 Primary Antibody for IHC (fro), WB - ABIN2475899
Goolamali, Evered, Shuster: Thyroid disease and sebaceous function. in British medical journal 1976
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Human Polyclonal NOD2 Primary Antibody for IP, WB - ABIN4340260
Chauhan, Marriott: Differential roles for NOD2 in osteoblast inflammatory immune responses to bacterial pathogens of bone tissue. in Journal of medical microbiology 2010
Human Polyclonal NOD2 Primary Antibody for ELISA, ICC - ABIN4340247
Rahman, Midtling, Svingen, Xiong, Bell, Tung, Smyrk, Egan, Faubion: The pathogen recognition receptor NOD2 regulates human FOXP3+ T cell survival. in Journal of immunology (Baltimore, Md. : 1950) 2010
Human Monoclonal NOD2 Primary Antibody for FACS, ICC - ABIN4340264
Subramanian, Bergman, Henriques-Normark: Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils. in Journal of innate immunity 2017
novel mechanisms allowing Leptospira interrogans to escape recognition by the NOD1 (show NOD1 Antibodies) and NOD2 receptors may be important in circumventing innate host responses
Studies results provide evidence that Crohn's disease patients have an impairment in mannose-binding lectin (show MBL2 Antibodies)-mannose-associated serine protease (show F2 Antibodies) functional activity and that this defect is associated with mannose-binding lectin 2 (show MBL2 Antibodies) and NOD2 variants.
blockage of RhoA (show RHOA Antibodies)/ROCK repressed the TAK1 (show MAP3K7 Antibodies)/NOD2-mediated NF-kappaB (show NFKB1 Antibodies) pathway in HaCaT cells exposed to UVB.
this study reports the phenotype of a kindred with Blau syndrome caused by a novel NOD2 mutation
Results demonstrate that NOD2 contributes to the regulation of blood monocytes.
The interplay between NOD2 signaling, proinflammatory cytokines, CHIT1 activity, heightened oxidative stress and DNA damage orchestrates allergic airway inflammation and thus contributing to the pathogenesis of atopic asthma.
The negative NOD2-smoking interaction in Crohn's disease is specific to the 1007fs variant. However, opposing rates of this variant and smoking across age at diagnosis may explain this negative interaction.
NOD2 up-regulates TLR2-mediated IL-23p19 (show IL23A Antibodies) expression via increasing c-Rel (show NFkBP65 Antibodies) activation in Paneth cell-like cells
Results demonstrate the leucine-rich repeat (LRR) domain of Nod2 is sufficient to bind to bacterial peptidoglycan fragments and defined critical residues on Nod2 responsible for recognition.
Our findings suggest that genetic variants in NOD2 are only associated with OFG in patients with concurrent intestinal disease.
In conclusion, the study indicates that Nod2-dependent responses account for Neospora caninum elimination. On the other hand, the inflammatory milieu induced by this innate receptor provoked pathogenesis and death in severe experimental neosporosis.
Results demonstrate that NOD2 contributes to the regulation of blood monocytes
Study for the first time demonstrates a novel role of NOD-2 signaling in differentiating bone marrow precursors to highly immunogenic dendritic cells.
NOD2 plays a critical role in the suppression of inflammation and tumorigenesis in the colon via downregulation of the TLR signaling pathways.
our data suggest that Nod2 plays a role in T1DM development. the role of the Nod2 gene contributes to alteration of the gut (show GUSB Antibodies) microbiota, nod2 acts as a recessive modulator in T1DM susceptibility.
Nod2 deletion improved both chronic cobblestone ileitis, as well as acute dextran sodium sulfate colitis in a murine model of spontaneous ileitis
Nod2-signaling is essentially involved in the well-balanced innate and adaptive immune responses upon Campylobacter jejuni infection of IL-10 (show IL10 Antibodies)(-/-) mice.
Chlamydophila pneumoniae cpn0423-induced cytokine response is mediated by host NOD2 during the infection.
we conclude that coordinate engagement of NOD2 and TLR2 constitutes a key step in the genesis of Lp-mediated protection from a lethal respiratory virus infection, and represents a critical target for modulation of virus-induced inflammatory pathology.
Results show that the simultaneous absence of Nod1 (show NOD1 Antibodies) and Nod2 is associated with accelerated T cell death upon alloantigen encounter, suggesting these proteins might provide new targets to ameliorate T cell responses in a variety of inflammatory states, including those associated with bone marrow or solid organ transplantation.
These results revealed that thermal stress increased the expression levels of NOD1 (show NOD1 Antibodies)/2 genes and acute inflammatory cytokines which sheds some light on their role on immune response of the host cells during thermal stress.These preliminary studies indicated that the immune-related genes differentially expressed during thermal stress among native and crossbred cattle.
Data indicate six single-nucleotide polymorphisms (SNPs) in the caspase recruitment domain 15 protein (CARD15) gene associated with susceptibility to bovine tuberculosis (BTB) in Chinese Holstein cows.
Data indicate that the Nod2 signaling adaptor protein (NOD2) G-->A at position 1594 bp plays a critical role in increasing 305-day milk yields.
Genetic variation and putative regulatory regions in bovine CARD15.
A significant association was found between two polymorphisms of CARD15 and paratuberculosis status; cows with the heterozygous genotype were 3.35 times more likely to be infected than cows with the reference genotype.
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.
caspase recruitment domain 15 protein
, NLR family, CARD domain containing 2
, NOD-like receptor C2
, caspase recruitment domain family, member 15
, caspase recruitment domain protein 15
, caspase recruitment domain-containing protein 15
, inflammatory bowel disease protein 1
, nucleotide-binding oligomerization domain 2
, nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2
, nucleotide-binding oligomerization domain-containing protein 2