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anti-Mouse (Murine) PELI2 Antibodies:
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E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. Not required for NF-kappa-B activation (By similarity).
E3 ubiquitin-protein ligase pellino homolog 2
, protein pellino homolog 2
, pellino homolog 2