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S100A14 is expressed in a subset of lung adenocarcinoma, and its expression is related to certain clinicopathological parameters. Furthermore, S100A14 expression was strongly correlated with migration and invasion in lung adenocarcinoma cells.
Increased S100A15 expression and decreased DNA methylation (show HELLS Proteins) of its gene promoter region were associated with high metastasis potential and poor outcome in lung adenocarcinoma.
results indicate that S100A14 may have a role in the induction of differentiation and inhibition of cell metastasis in gastric cancer.
We identified a two-gene signature including KCNN4 (show KCNN4 Proteins) and S100A14 which was related to recurrence in optimally debulked serous ovarian carcinoma patients
Co-expression of S100A14 and S100A16 (show S100A16 Proteins) correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion
The antimicrobial peptides psoriasin (S100A7 (show S100A7 Proteins)) and koebnerisin (S100A15) suppress extracellular matrix production and proliferation of human fibroblasts
S100A14 is expressed in epithelial-like, but not in mesenchymal-like, triple-negative breast cancer cells in vitro.
Data show that the genetic variant 425G>A on the 5'-UTR of calcium-binding protein (show CETN1 Proteins) S100A14 was associated with reduced S100A14 expression in gastric cancer (GC) cells.
Data indicate that S100A14 has a crucial role in EOC progression, and its overexpression is associated with poor prognosis.
Data demonstrate that S100A14 is transcriptionally regulated by JunB (show JUNB Proteins) and involved in esophageal squamous cell carcinoma cell differentiation.
This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828).
S100 calcium-binding protein A14
, breast cancer membrane protein 84
, protein S100-A14
, S100 calcium binding protein A15
, S100 calcium binding protein A14