alpha Defensin 1 Products
(Defensin, alpha 1 (DEFA1))
Categories
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. [provided by RefSeq, May 2010].
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Featured alpha Defensin 1 Categories
alpha Defensin 1 Antibodies
High quality antibodies with extensive validation data.
alpha Defensin 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
alpha Defensin 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended alpha Defensin 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IF, WB
Validations
- (3)
Cat. No.
ABIN6139522
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, ICC, IHC (fro), IHC (p), WB
Validations
- (2)
Cat. No.
ABIN7433975
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
ICC, IHC, IP, WB
Validations
- (2)
Cat. No.
ABIN7433978
Quantity
100 μL
Datasheet
Datasheet
Recommended alpha Defensin 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955300
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955301
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955302
Quantity
96 tests
Datasheet
Datasheet
Recommended alpha Defensin 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351408
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2719348
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7412398
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our alpha Defensin 1 products
: "HNP-1 and HBD-1 as Biomarkers for the Immune Systems of Elite Basketball Athletes." in: Antibiotics (Basel, Switzerland), Vol. 9, Issue 6, (2020) (PubMed).: "Leukotriene B4 is essential for lung host defence and alpha-defensin-1 production during Achromobacter xylosoxidans infection." in: Scientific reports, Vol. 7, Issue 1, pp. 17658, (2019) (PubMed).
: "Cerebrospinal fluid biomarker candidates associated with human WNV neuroinvasive disease." in: PLoS ONE, Vol. 9, Issue 4, pp. e93637, (2014) (PubMed).
: "Tuberculin skin test and interferon-gamma release assay values are associated with antimicrobial peptides expression in polymorphonuclear cells during latent tuberculous infection." in: Memórias do Instituto Oswaldo Cruz, Vol. 109, Issue 3, pp. 330-4, (2014) (PubMed).
: "Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity." in: The Journal of clinical investigation, Vol. 115, Issue 3, pp. 765-73, (2005) (PubMed).
Synonyms and alternative names related to alpha Defensin 1
defensin alpha 1 (DEFA1), defensin, alpha 1 (Defa1), defensin, alpha 1 (DEFA1), defensin alpha 5 (Defa5), alpha-defensin 1A (MNP1A), defensin 1 (Def1), Def, DEF1, Defa, DEFA1, DEFA2, Defcr, Defcr1, GB19392, HNP-1, HP-1, HP1, MRSProtein level used designations for alpha Defensin 1
- defensin, alpha 1, myeloid-related sequence
- defensin, alpha 2
- myeloid-related sequence
- neutrophil defensin 1
- alpha-defensin 1
- cryptdin-1
- defensin related cryptdin peptide 1
- defensin-1
- defensin-related cryptdin peptide
- defensin alpha 1
- Paneth cell-specific alpha-defensin 2
- alpha-defensin 5, Paneth cell-specific
- defensin NP-2
- neutrophil antibiotic peptide NP-1
- neutrophil antibiotic peptide NP-2
- neutrophil defensin 2
- ratNP-1
- ratNP-2
- Neutrophil defensin 1
- Neutrophil defensin 3
- RMAD-1
- RMAD-3
- RMAD-8
- neutrophil defensin 8
- royalisin
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